Diltiazem hydrochloride and Paroxetine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diltiazem hydrochloride (diltiazem hydrochloride) and Paroxetine hydrochloride (paroxetine hydrochloride). Common drug interactions include dehydration among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Diltiazem hydrochloride and Paroxetine hydrochloride. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Diltiazem hydrochloride?

Diltiazem hydrochloride has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 14,897 Diltiazem hydrochloride users. Check the latest studies of Diltiazem hydrochloride.

What is Paroxetine hydrochloride?

Paroxetine hydrochloride has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 10,426 Paroxetine hydrochloride users. Check the latest studies of Paroxetine hydrochloride.



On Jul, 14, 2026

34 people who take Diltiazem hydrochloride and Paroxetine hydrochloride together, and have interactions are studied.

Diltiazem hydrochloride and Paroxetine hydrochloride drug interactions.

What are the common drug interactions of Diltiazem Hydrochloride and Paroxetine Hydrochloride, by gender? *:

female:

  1. Dehydration (dryness resulting from the removal of water)
  2. Drug intolerance (drug sensitivity)
  3. Fatigue (feeling of tiredness)
  4. Haemoglobin decreased
  5. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  6. Rectal haemorrhage (bleeding from anus)
  7. Renal failure (kidney dysfunction)
  8. Skin discolouration (change of skin colour)
  9. Weight decreased
  10. Abdominal discomfort

male:

  1. Anaemia (lack of blood)
  2. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  3. Hyperglycaemia (high blood sugar)
  4. Blood potassium decreased
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Blood glucose increased
  7. Cardiac failure
  8. Completed suicide (act of taking one's own life)
  9. Confusional state
  10. Death

What are the common drug interactions of Diltiazem Hydrochloride and Paroxetine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  2. Accidental needle stick
  3. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  4. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  5. Chronic kidney disease
  6. Completed suicide (act of taking one's own life)
  7. Coronary artery stenosis (narrowing of coronary artery)
  8. Cytolytic hepatitis (dissolution or destruction of a liver cell)
  9. Drug abuse
  10. Drug toxicity

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Anaemia (lack of blood)
  3. Hyperglycaemia (high blood sugar)
  4. Blood potassium decreased
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Blood glucose increased
  7. Cardiac failure
  8. Fatigue (feeling of tiredness)
  9. Haemoglobin decreased
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 17.65%
  2. Lung Cancer - Non-Small Cell (lung cancer): 5 people, 14.71%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 8.82%
  4. Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 2 people, 5.88%
  5. High Blood Cholesterol: 2 people, 5.88%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.88%
  7. Asthma: 2 people, 5.88%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Diltiazem hydrochloride and Paroxetine hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diltiazem hydrochloride and Paroxetine hydrochloride:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diltiazem hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paroxetine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diltiazem hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paroxetine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride and paroxetine hydrochloride (the active ingredients of Diltiazem hydrochloride and Paroxetine hydrochloride, respectively), and Diltiazem hydrochloride and Paroxetine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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