Diovan hct and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diovan hct (hydrochlorothiazide; valsartan) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include arthropathy among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Diovan hct and Arthrotec. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Diovan hct?

Diovan hct has active ingredients of hydrochlorothiazide; valsartan. It is often used in high blood pressure. eHealthMe is studying from 6,093 Diovan hct users. Check the latest studies of Diovan hct.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

On Jul, 19, 2026

23 people who take Diovan hct and Arthrotec together, and have interactions are studied.

Diovan hct and Arthrotec drug interactions.

What are the common drug interactions of Diovan Hct and Arthrotec, by gender? *:

female:

Arthropathy
Bone disorder
Bone pain
Cataract (clouding of the lens inside the eye)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Fracture delayed union (delayed cure of broken bone)
Humerus fracture (injury to the upper arm bone)
Osteoporosis (bones weak and more likely to break)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)

male:

Chills (felling of cold)
Pyrexia (fever)
Pain in extremity
Escherichia infection (bacterial infection by escherichia coli)
Fibromyalgia (a long-term condition which causes pain all over the body)
Intervertebral disc degeneration (spinal disc degeneration)
Memory impairment
Painful respiration
Ascites (accumulation of fluid in the abdominal cavity)
Back pain

What are the common drug interactions of Diovan Hct and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arthropathy
Bone disorder
Bone pain
Cataract (clouding of the lens inside the eye)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Fracture delayed union (delayed cure of broken bone)
Humerus fracture (injury to the upper arm bone)
Osteoporosis (bones weak and more likely to break)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)

20-29:

n/a

30-39:

n/a

40-49:

Anaemia postoperative
Arthralgia (joint pain)
Arthropathy
Device failure
Fall
Femur fracture
Fracture nonunion (permanent failure of healing following a broken bone)
Gait disturbance
Homicidal ideation (thoughts about human killing another human)
Immobile (not moving)

50-59:

Drug hypersensitivity
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Infusion related reaction
Laryngeal oedema (swelling of larynx)
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

60+:

Chills (felling of cold)
Escherichia infection (bacterial infection by escherichia coli)
Pyrexia (fever)
Drug ineffective
Headache (pain in head)
Intervertebral disc degeneration (spinal disc degeneration)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 60.87%
Gait Disturbance: 7 people, 30.43%
Depression: 3 people, 13.04%
Thyroid Diseases: 2 people, 8.70%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 8.70%
Osteoporosis (bones weak and more likely to break): 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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