Diovan and Butrans drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diovan (valsartan) and Butrans (buprenorphine). Common drug interactions include application site burn among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Diovan and Butrans. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,154 Diovan users. Check the latest studies of Diovan.

What is Butrans?

Butrans has active ingredients of buprenorphine. It is often used in pain. eHealthMe is studying from 64,148 Butrans users. Check the latest studies of Butrans.

On Aug, 11, 2026

30 people who take Diovan and Butrans together, and have interactions are studied.

What are the common drug interactions of Diovan and Butrans, by gender? *:

female:

Application site burn
Application site vesicles (small bubble within a cell at application site)
Chronic kidney disease
Pain in extremity
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Alopecia (absence of hair from areas of the body)
Fall
Renal failure (kidney dysfunction)
Application site exfoliation (application site removal of the oldest dead skin cells on the skin's outermost surface)

male:

Anaemia (lack of blood)
Arthralgia (joint pain)
Confusional state
Crying
Drug dependence
Drug diversion
Fall
Hallucination (an experience involving the perception of something not present)
Intervertebral disc protrusion (spinal disc protrusion)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

What are the common drug interactions of Diovan and Butrans, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Cardiac disorder
Crying
Drug dependence
Drug diversion
Heart rate increased
Infusion related reaction
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Osteomyelitis (infection of bone)
Oxygen saturation decreased

50-59:

Chronic kidney disease
Alopecia (absence of hair from areas of the body)
Hot flush (sudden feelings of heat)
Priapism (prolonged and painful erection that can last from several hours up to a few days)
Renal failure (kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Stress
Vision blurred

60+:

Anaemia (lack of blood)
Epistaxis (bleed from the nose)
Blood pressure fluctuation
Drug ineffective
Aphasia (damage to the parts of the brain that control language)
Back pain
Cardiac failure congestive
Cellulitis (infection under the skin)
Confusional state
Device related infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 13.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 13.33%
Gout (uric acid crystals building up in the body): 3 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 10.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 10.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.67%
Osteoporosis (bones weak and more likely to break): 2 people, 6.67%
Neuropathy Peripheral (surface nerve damage): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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