Diovan and Methyldopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diovan (valsartan) and Methyldopa (methyldopa). Common drug interactions include loss of consciousness among females and left ventricular hypertrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Diovan and Methyldopa. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

On Jul, 19, 2026

88 people who take Diovan and Methyldopa together, and have interactions are studied.

Diovan and Methyldopa drug interactions.

What are the common drug interactions of Diovan and Methyldopa, by gender? *:

female:

Loss of consciousness
Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)
Neck pain
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
Renal impairment (severely reduced kidney function)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Dysarthria (speech disorder)

male:

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Tricuspid valve incompetence (inefficient heart valve)
Blood creatinine increased
Headache (pain in head)
Heart rate increased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Infantile apnoeic attack (episodes where breathing stops temporarily in infant)

What are the common drug interactions of Diovan and Methyldopa, by age (0-1 to 60+)? *:

0-1:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
Low birth weight baby
Neonatal disorder (disease of neonates)
Premature baby

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Abortion (termination of pregnancy)
Drug exposure during pregnancy
Back pain
Maternal exposure during pregnancy (use of substance during pregnancy)
Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
Amniotic fluid volume decreased
Intra-uterine death
Polyhydramnios (excess of amniotic fluid in the amniotic sac)
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)

40-49:

Glomerulosclerosis (a hardening of the glomerulus in the kidney)
Headache (pain in head)
Heart rate increased
Nausea (feeling of having an urge to vomit)
Visual impairment
Angiopathy (generic term for a disease of the blood vessels)
Blood creatinine increased
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Nephropathy (damage to or disease of a kidney)
Renal arteriosclerosis (a thickening and hardening of arteries of kidney)

50-59:

Abdominal pain
Anaemia (lack of blood)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Haematochezia (passage of stools containing blood)
Hepatitis a
Hepatitis a antibody positive
Neck pain
Painful defaecation
Blood glucose increased

60+:

Urinary tract infection
Fall
Hypertensive encephalopathy (neurological dysfunction induced by malignant hypertension)
Memory impairment
Pneumonia
Weight decreased
Arthralgia (joint pain)
Blood pressure fluctuation
Decreased appetite
Drug ineffective

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 11.36%
High Blood Cholesterol: 8 people, 9.09%
Depression: 6 people, 6.82%
Diabetes: 5 people, 5.68%

* Approximation only. Some reports may have incomplete information.

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