Diovan and Microzide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diovan (valsartan) and Microzide (hydrochlorothiazide). Common drug interactions include back pain among females and obsessive-compulsive disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Diovan and Microzide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.

What is Microzide?

Microzide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 994 Microzide users. Check the latest studies of Microzide.

On Jul, 14, 2026

17 people who take Diovan and Microzide together, and have interactions are studied.

What are the common drug interactions of Diovan and Microzide, by gender? *:

female:

Back pain
Blood potassium decreased
Blood sodium decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic kidney disease
Constipation
Diarrhoea
Drug effect decreased
Drug ineffective

male:

Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pathological gambling
Heart rate increased
Heart rate irregular
Hyperglycaemia (high blood sugar)
Hyperhidrosis (abnormally increased sweating)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Joint swelling
Pain in extremity
Sedation

What are the common drug interactions of Diovan and Microzide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Constipation
Large intestine perforation (hole in large intestine)

50-59:

Chest pain
Urinary tract infection

60+:

Blood potassium decreased
Blood sodium decreased
Joint swelling
Malaise (a feeling of general discomfort or uneasiness)
Pain in extremity
Renal failure (kidney dysfunction)
Sedation
Speech disorder
Tongue paralysis (loss of function of tongue)
Weakness

What are the existing conditions these people have? *

Pain: 6 people, 35.29%
Stress And Anxiety: 6 people, 35.29%
Diabetes: 5 people, 29.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 29.41%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 23.53%
Magnesium Deficiency (lack of magnesium): 4 people, 23.53%
Anaemia (lack of blood): 4 people, 23.53%
Blood Magnesium Decreased: 4 people, 23.53%
Bowel Movement Irregularity: 4 people, 23.53%
Cardiac Disorder: 4 people, 23.53%

* Approximation only. Some reports may have incomplete information.

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