Diphen and Cabergoline drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Diphen (diphenhydramine hydrochloride) and Cabergoline (cabergoline). Common drug interactions include gastrointestinal infection among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Diphen and Cabergoline. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Diphen?
Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.
What is Cabergoline?
Cabergoline has active ingredients of cabergoline. It is often used in prolactinoma. eHealthMe is studying from 6,257 Cabergoline users. Check the latest studies of Cabergoline.
34 people who take Diphen and Cabergoline together, and have interactions are studied.

What are the common drug interactions of Diphen and Cabergoline, by gender? *:
female:
- Gastrointestinal infection (infection of stomach and intestine)
- Infusion site pain
- Infusion site pruritus (severe itching at infusion site)
- Infusion site swelling
- Viral infection
- Infusion site haemorrhage (bleeding from infusion site)
- Small intestinal obstruction (blockage in small intestine)
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
- Arrhythmia (irregular heartbeat)
- Arthropathy
male:
- Back pain
- Diarrhoea
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Nausea (feeling of having an urge to vomit)
- Vertigo
What are the common drug interactions of Diphen and Cabergoline, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Haemoglobin decreased
- Lymphocyte count decreased
- Thrombocytopenia (decrease of platelets in blood)
30-39:
- Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
- Dehydration (dryness resulting from the removal of water)
- Gastrointestinal infection (infection of stomach and intestine)
- Infusion site pain
- Infusion site pruritus (severe itching at infusion site)
- Infusion site swelling
- Viral infection
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Infusion site haemorrhage (bleeding from infusion site)
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
40-49:
- Urinary tract infection
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Hospitalisation
- Sinusitis (inflammation of sinus)
- Skin infection
- Infusion site reaction
- Nasopharyngitis (inflammation of the nasopharynx)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Blood pressure increased
50-59:
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Joint injury
- Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
- Pneumonia viral
- Pruritus (severe itching of the skin)
- Upper respiratory tract infection
60+:
- Anaemia (lack of blood)
- Arrhythmia (irregular heartbeat)
- Infection
- Intestinal obstruction
- Iritis (painful inflammation of the iris of the eye)
- Ocular hypertension (intraocular pressure higher than normal)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pulmonary thrombosis (scarring in the lungs)
- Sinusitis (inflammation of sinus)
- Small intestinal obstruction (blockage in small intestine)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 14 people, 41.18%
- Immunodeficiency: 6 people, 17.65%
- Asthma: 3 people, 8.82%
- Nausea (feeling of having an urge to vomit): 2 people, 5.88%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.88%
- Immune System Disorder: 2 people, 5.88%
- Hiv Infection: 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Diphen and Cabergoline?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Diphen (115,432 reports)
- Cabergoline (6,257 reports)
Browse all drug interactions of Diphen and Cabergoline:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Diphen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cabergoline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diphen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cabergoline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gürbüz F, Ya?c?-Küpeli B, K?r Y, Yüksel B, Zorludemir S, Gürbüz BB, Küpeli S, "The first report of cabergoline-induced immune hemolytic anemia in an adolescent with prolactinoma", Journal of Pediatric Endocrinology and Metabolism, 2014 Jan .
- Harris YT, Harris AZ, "Cabergoline associated with first episode mania", Psychosomatics, 2012 Jan .
- Gürbüz F, Ya?c?-Küpeli B, K?r Y, Yüksel B, Zorludemir S, Gürbüz BB, Küpeli S, "The first report of cabergoline-induced immune hemolytic anemia in an adolescent with prolactinoma", Journal of Pediatric Endocrinology and Metabolism, 2014 Jan .
- Harris YT, Harris AZ, "Cabergoline associated with first episode mania", Psychosomatics, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on diphenhydramine hydrochloride and cabergoline (the active ingredients of Diphen and Cabergoline, respectively), and Diphen and Cabergoline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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