Diphen and Echinacea angustifolia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diphen (diphenhydramine hydrochloride) and Echinacea angustifolia (echinacea). Common drug interactions include blood pressure fluctuation among females and prostatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Diphen and Echinacea angustifolia. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.

What is Echinacea angustifolia?

Echinacea angustifolia has active ingredients of echinacea. eHealthMe is studying from 65 Echinacea angustifolia users. Check the latest studies of Echinacea angustifolia.

On Jul, 20, 2026

15 people who take Diphen and Echinacea angustifolia together, and have interactions are studied.

Diphen and Echinacea angustifolia drug interactions.

What are the common drug interactions of Diphen and Echinacea Angustifolia, by gender? *:

female:

Blood pressure fluctuation
Blood pressure increased
Blood pressure systolic increased
Chest pain
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Drug hypersensitivity
Electrolyte imbalance
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Heart rate increased
Hypotension (abnormally low blood pressure)

male:

Prostatitis (inflammation of the prostate gland)
Cough
Nerve compression
Pneumonia
Surgery

What are the common drug interactions of Diphen and Echinacea Angustifolia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Anaphylactic reaction (serious allergic reaction)
Blood pressure fluctuation
Blood pressure increased
Blood pressure systolic increased
Chest pain
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Drug hypersensitivity
Electrolyte imbalance
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

40-49:

n/a

50-59:

n/a

60+:

Prostatitis (inflammation of the prostate gland)
Cough
Nerve compression
Pneumonia
Rash pruritic (redness with itching)
Sinus disorder (disease of sinus)
Surgery

What are the existing conditions these people have? *

Vasculitis (inflammation of a blood vessel or blood vessels): 6 people, 40.00%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 4 people, 26.67%
Combined Immunodeficiency: 4 people, 26.67%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
Immunodeficiency Common Variable: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Diphen and Echinacea angustifolia?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously