Diphen and Maxitrol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Diphen (diphenhydramine hydrochloride) and Maxitrol (dexamethasone; neomycin sulfate; polymyxin b sulfate). Common drug interactions include anxiety among females and urinary tract infection staphylococcal among males.
The phase IV clinical study analyzes what interactions people have when they take Diphen and Maxitrol. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Diphen?
Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.
What is Maxitrol?
Maxitrol has active ingredients of dexamethasone; neomycin sulfate; polymyxin b sulfate. eHealthMe is studying from 986 Maxitrol users. Check the latest studies of Maxitrol.
23 people who take Diphen and Maxitrol together, and have interactions are studied.

What are the common drug interactions of Diphen and Maxitrol, by gender? *:
female:
- Anxiety
- Road traffic accident
- Visual impairment
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Arthralgia (joint pain)
- Back pain
- Catheter site pain
- Chest discomfort
- Dizziness
male:
- Urinary tract infection staphylococcal
- Anaemia (lack of blood)
- Haematuria (presence of blood in urine)
- Penile pain
- Renal tubular necrosis (death of kidney tubules)
- Staphylococcus test positive
- Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)
- Urinary tract infection
- Weight decreased
- Arteriovenous fistula
What are the common drug interactions of Diphen and Maxitrol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaphylactic reaction (serious allergic reaction)
- Skin exfoliation (removal of the oldest dead skin cells)
- Urticaria (rash of round, red welts on the skin that itch intensely)
50-59:
- Agitation (state of anxiety or nervous excitement)
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Blindness transient (sudden loss of vision)
- Choking sensation (feeling of obstruction in respiratory system)
- Contusion (a type of hematoma of tissue in which capillaries)
- Dermatillomania (skin picking disorders)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Drug hypersensitivity
60+:
- Fatigue (feeling of tiredness)
- Anaemia (lack of blood)
- Complications of transplanted kidney
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Eye disorder
- Fall
- Foot fracture
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
What are the existing conditions these people have? *
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 21.74%
- Hypersensitivity: 3 people, 13.04%
- Breast Cancer: 3 people, 13.04%
- Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.70%
- Swelling Face: 2 people, 8.70%
- Spinal Stenosis (narrowing of spinal column): 2 people, 8.70%
- Pain: 2 people, 8.70%
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 8.70%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.70%
- Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Diphen and Maxitrol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Diphen and Maxitrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Diphen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Maxitrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diphen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxitrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on diphenhydramine hydrochloride and dexamethasone; neomycin sulfate; polymyxin b sulfate (the active ingredients of Diphen and Maxitrol, respectively), and Diphen and Maxitrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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