Diphen and Pectin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diphen (diphenhydramine hydrochloride) and Pectin (pectin). Common drug interactions include arthralgia among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Diphen and Pectin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.

What is Pectin?

Pectin has active ingredients of pectin. eHealthMe is studying from 293 Pectin users. Check the latest studies of Pectin.



On Jul, 19, 2026

20 people who take Diphen and Pectin together, and have interactions are studied.

Diphen and Pectin drug interactions.

What are the common drug interactions of Diphen and Pectin, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Lung disorder (lung disease)
  4. Cough
  5. Lower respiratory tract infection
  6. Oropharyngeal pain
  7. Rhinorrhoea (watery mucus discharge from the nose)
  8. Pain
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Blood pressure increased

male:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Anaemia (lack of blood)
  3. Lymphadenopathy (disease or enlargement of lymph nodes)
  4. Lymphatic obstruction (blockage in lymphatic duct)
  5. Pain
  6. Pleural effusion (water on the lungs)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Urinary tract infection staphylococcal
  10. Neutropenia (an abnormally low number of neutrophils)

What are the common drug interactions of Diphen and Pectin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Asthma

20-29:

n/a

30-39:

n/a

40-49:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Anaemia (lack of blood)
  3. Cellulitis (infection under the skin)
  4. Dehydration (dryness resulting from the removal of water)
  5. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Hydronephrosis (water inside the kidney)
  8. Hypokalaemia (low potassium)
  9. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  10. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

50-59:

n/a

60+:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Arthralgia (joint pain)
  3. Rhinorrhoea (watery mucus discharge from the nose)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Back pain
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Infusion site pruritus (severe itching at infusion site)
  10. Infusion site swelling

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 6 people, 30.00%
  2. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 10.00%
  3. Cystic Fibrosis (disease of the secretary glands): 2 people, 10.00%
  4. Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.00%
  5. Pain: 1 person, 5.00%
  6. Multiple Myeloma (cancer of the plasma cells): 1 person, 5.00%
  7. Immunodeficiency: 1 person, 5.00%
  8. Hypokalemia (low potassium): 1 person, 5.00%
  9. Hyperkalemia (damage to or disease of the kidney): 1 person, 5.00%
  10. Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Diphen and Pectin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diphen and Pectin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pectin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diphen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pectin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and pectin (the active ingredients of Diphen and Pectin, respectively), and Diphen and Pectin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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