Diphen and Scenesse drug interactions - a phase IV clinical study of FDA data

Summary:

We study 115,443 people who take Diphen (diphenhydramine hydrochloride) and Scenesse (afamelanotide). There is no drug interaction reported.

The study analyzes what interactions people have when they take Diphen and Scenesse. It is created by eHealthMe based on reports the from the FDA, and is updated regularly.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,429 Diphen users. Check the latest studies of Diphen.

What is Scenesse?

Scenesse has active ingredients of afamelanotide. eHealthMe is studying from 14 Scenesse users. Check the latest studies of Scenesse.



On Dec, 29, 2025

No report is found.

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How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and afamelanotide (the active ingredients of Diphen and Scenesse, respectively), and Diphen and Scenesse (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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