Diphen and Tetrabenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diphen (diphenhydramine hydrochloride) and Tetrabenazine (tetrabenazine). Common drug interactions include aggression among females and electrocardiogram qt prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Diphen and Tetrabenazine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.

What is Tetrabenazine?

Tetrabenazine has active ingredients of tetrabenazine. eHealthMe is studying from 1,580 Tetrabenazine users. Check the latest studies of Tetrabenazine.

On Jul, 16, 2026

11 people who take Diphen and Tetrabenazine together, and have interactions are studied.

Diphen and Tetrabenazine drug interactions.

What are the common drug interactions of Diphen and Tetrabenazine, by gender? *:

female:

Aggression
Diarrhoea
Drug ineffective
Eye pain
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Influenza
Intentional self-injury
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nasopharyngitis (inflammation of the nasopharynx)

male:

Electrocardiogram qt prolonged
Suicidal ideation
Dysphagia (a condition in which swallowing is difficult or painful)
Dystonia (abnormal muscle tone)
Speech disorder
Tardive dyskinesia (a disorder that involves involuntary movements)
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Constipation
Disturbance in attention
Dry mouth

What are the common drug interactions of Diphen and Tetrabenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Electrocardiogram qt prolonged
Suicidal ideation
Weight increased
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Blood prolactin increased
Depression
Galactorrhoea (secretion of breast milk in men)
Lethargy (tiredness)
Feeling of despair
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

20-29:

Aggression
Drug ineffective
Intentional self-injury
Screaming (a long loud piercing cry)

30-39:

n/a

40-49:

Dyskinesia (abnormality or impairment of voluntary movement)
Dysphagia (a condition in which swallowing is difficult or painful)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fall
Grunting (abnormal, short, deep, hoarse sounds in exhalation that often accompany severe chest pain)
Neck pain
Oromandibular dystonia (affecting the ability to chew, speak and swallow)
Sedation
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
Urinary hesitation (difficulty in beginning the flow of urine)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Gilles De La Tourette Syndrome (a condition that causes people to make repeated, quick movements or sounds that they cannot control): 5 people, 45.45%
Tardive Dyskinesia (a disorder that involves involuntary movements): 4 people, 36.36%
Stress And Anxiety: 4 people, 36.36%
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 2 people, 18.18%
Weight Loss: 1 person, 9.09%
Weight Increased: 1 person, 9.09%
Speech Disorder: 1 person, 9.09%
Oral Disorder (mouth disease): 1 person, 9.09%
Oesophageal Spasm (contraction of oesophagus): 1 person, 9.09%
Movement - Unpredictable Or Jerky: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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