Diprivan and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprivan (propofol) and Melatonin (melatonin). Common drug interactions include abdominal abscess among females and fluid overload among males.

The phase IV clinical study analyzes what interactions people have when they take Diprivan and Melatonin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Jul, 08, 2026

26 people who take Diprivan and Melatonin together, and have interactions are studied.

Diprivan and Melatonin drug interactions.

What are the common drug interactions of Diprivan and Melatonin, by gender? *:

female:

Abdominal abscess (collection of pus in abdomen)
Anastomotic leak
Ileal stenosis (obstruction in the ileal)
Abdominal pain
Alanine aminotransferase increased
Ankle fracture
Aspartate aminotransferase increased
Cardiac arrest
Chronic kidney disease
Confusional state

male:

Fluid overload (too much fluid in the blood)
Hyperkalaemia (damage to or disease of the kidney)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematuria (presence of blood in urine)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Nephrolithiasis (calculi in the kidneys)

What are the common drug interactions of Diprivan and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cerebral hypoperfusion (a condition in which the brain doesn't get enough blood)
Encephalitis (inflammation of the brain)
Hydrocephalus (water on the brain)
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Lipase increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cardiac arrest

10-19:

Abdominal abscess (collection of pus in abdomen)
Anastomotic leak
Ileal stenosis (obstruction in the ileal)
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Drug resistance (reduction in effectiveness of a drug)
Emotional distress
Foot fracture
Hand fracture
Pain
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

30-39:

Abdominal pain
Confusional state
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nausea (feeling of having an urge to vomit)
Right ventricular failure (right half of the heart fails to work)
Septic shock (shock due to blood infection)
Skin wound
Somnolence (a state of near-sleep, a strong desire for sleep)
Vomiting

40-49:

n/a

50-59:

Fluid overload (too much fluid in the blood)
Hyperkalaemia (damage to or disease of the kidney)
Hypoxia (low oxygen in tissues)
Abdominal distension
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiogenic shock (inadequate circulation of blood)
Cellulitis (infection under the skin)
Dizziness
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Small intestinal obstruction (blockage in small intestine)
Ankle fracture
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Death
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Platelet count decreased

What are the existing conditions these people have? *

Pain: 8 people, 30.77%
Constipation: 6 people, 23.08%
Sleep Disorder: 5 people, 19.23%
Nausea (feeling of having an urge to vomit): 5 people, 19.23%
High Blood Pressure: 5 people, 19.23%
Cough: 4 people, 15.38%
Flatulence (flatus expelled through the anus): 4 people, 15.38%
Stress And Anxiety: 3 people, 11.54%
Dehydration (dryness resulting from the removal of water): 3 people, 11.54%
Diarrhea: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Diprivan and Melatonin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously