Diprivan and Sandimmune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprivan (propofol) and Sandimmune (cyclosporine). Common drug interactions include multi-organ failure among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Diprivan and Sandimmune. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

What is Sandimmune?

Sandimmune has active ingredients of cyclosporine. eHealthMe is studying from 6,694 Sandimmune users. Check the latest studies of Sandimmune.



On Jul, 29, 2026

14 people who take Diprivan and Sandimmune together, and have interactions are studied.

Diprivan and Sandimmune drug interactions.

What are the common drug interactions of Diprivan and Sandimmune, by gender? *:

female:

  1. Multi-organ failure (multisystem organ failure)
  2. Graft dysfunction
  3. Haemorrhage (bleeding)
  4. Lung transplant rejection (failure of lung transplant)
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Renal failure (kidney dysfunction)
  7. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  8. Blood pressure increased
  9. Immunosuppressant drug level increased
  10. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

  1. Insomnia (sleeplessness)
  2. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  3. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  4. Haematuria (presence of blood in urine)
  5. Headache (pain in head)
  6. Hypercapnia (too much smoke)
  7. Hypertension (high blood pressure)
  8. Immune system disorder
  9. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  10. Pain

What are the common drug interactions of Diprivan and Sandimmune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  2. Anaemia (lack of blood)
  3. Multi-organ failure (multisystem organ failure)
  4. Pneumonia
  5. Respiratory failure (inadequate gas exchange by the respiratory system)

10-19:

n/a

20-29:

  1. Blood pressure increased
  2. Communication disorder (speech and language disorder)
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Dyspnoea (difficult or laboured respiration)
  5. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  6. Headache (pain in head)
  7. Hypercapnia (too much smoke)
  8. Insomnia (sleeplessness)
  9. Laryngeal oedema (swelling of larynx)
  10. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)

30-39:

n/a

40-49:

  1. Graft dysfunction
  2. Haemorrhage (bleeding)
  3. Lung transplant rejection (failure of lung transplant)
  4. Multi-organ failure (multisystem organ failure)
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Renal failure (kidney dysfunction)

50-59:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

60+:

  1. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  2. Blood lactate dehydrogenase increased
  3. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  4. Haematuria (presence of blood in urine)
  5. Hypertension (high blood pressure)
  6. Immune system disorder
  7. Pain
  8. Renal failure (kidney dysfunction)
  9. Respiratory disorder (respiratory disease)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

  1. Interstitial Lung Disease: 4 people, 28.57%
  2. Insomnia (sleeplessness): 3 people, 21.43%
  3. Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 21.43%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
  5. High Blood Pressure: 1 person, 7.14%
  6. Candiduria (candida in urine): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Diprivan and Sandimmune?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diprivan and Sandimmune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diprivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sandimmune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diprivan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sandimmune and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on propofol and cyclosporine (the active ingredients of Diprivan and Sandimmune, respectively), and Diprivan and Sandimmune (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: