Diprivan and Tagamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprivan (propofol) and Tagamet (cimetidine). Common drug interactions include facial neuralgia among females and renal failure acute among males.

The phase IV clinical study analyzes what interactions people have when they take Diprivan and Tagamet. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

On Jul, 26, 2026

70 people who take Diprivan and Tagamet together, and have interactions are studied.

What are the common drug interactions of Diprivan and Tagamet, by gender? *:

female:

Facial neuralgia (pain of face)
Foot fracture
Generalised oedema (swelling all over the body)
Gingival infection (gum infection)
Gingival pain (gum pain)
Gingival swelling (gums swelling)
Gingivitis (inflammation of gums)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Humerus fracture (injury to the upper arm bone)
Joint dislocation (a joint position is changed from normal position)

male:

Renal failure acute (rapid kidney dysfunction)
Anaemia (lack of blood)
Abdominal distension
Acquired cardiac septal defect (hole in the heart)
Apnoea (suspension of external breathing)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Atrioventricular block second degree (heart block second degree)

What are the common drug interactions of Diprivan and Tagamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Hypotension (abnormally low blood pressure)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Hyperglycaemia (high blood sugar)
Pleural effusion (water on the lungs)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Renal impairment (severely reduced kidney function)
White blood cell count decreased
Altered state of consciousness (altered state of mind)
Cyst (a closed sac)

30-39:

Renal failure acute (rapid kidney dysfunction)
Blood bicarbonate decreased
Blood ph decreased
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Depressed level of consciousness
Haemoglobin decreased
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Mydriasis (a dilation of the pupil)

40-49:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Face oedema (swelling of face)
Pyrexia (fever)
Rash pustular (redness with pustules)
Tryptase increased
Anaphylactic reaction (serious allergic reaction)
Blood pressure decreased
Pruritus (severe itching of the skin)
Rash generalised (rash on most of body parts)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)

50-59:

Humerus fracture (injury to the upper arm bone)
Joint dislocation (a joint position is changed from normal position)
Lung disorder (lung disease)
Malocclusion (a misalignment)
Metastatic neoplasm (spreadable cancer tumour)
Mouth ulceration (mouth ulcers)
Oedema peripheral (superficial swelling)
Osteitis (a general term for inflammation of bone)
Osteitis deformans (a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

Renal failure acute (rapid kidney dysfunction)
Anaemia (lack of blood)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Atrioventricular block second degree (heart block second degree)
Blood glucose increased
Bradycardia (abnormally slow heart action)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 38.57%
Osteoporosis (bones weak and more likely to break): 27 people, 38.57%
Thrombocytopenia (decrease of platelets in blood): 11 people, 15.71%
Anaesthesia: 8 people, 11.43%
Uterine Atony (failure of the uterus to contract following delivery): 6 people, 8.57%
Postpartum Haemorrhage (bleeding in woman after she has given birth): 6 people, 8.57%
Pain: 6 people, 8.57%
High Blood Pressure: 5 people, 7.14%
Type 2 Diabetes: 4 people, 5.71%
Dyslipidaemia (abnormal amount of lipids): 4 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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