Diprolene and Percocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprolene (betamethasone dipropionate) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include adrenal insufficiency among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Diprolene and Percocet. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Diprolene?

Diprolene has active ingredients of betamethasone dipropionate. eHealthMe is studying from 1,048 Diprolene users. Check the latest studies of Diprolene.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

On Aug, 07, 2026

57 people who take Diprolene and Percocet together, and have interactions are studied.

Diprolene and Percocet drug interactions.

What are the common drug interactions of Diprolene and Percocet, by gender? *:

female:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Arthralgia (joint pain)
Asthma
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bullous lung disease
Erythema (redness of the skin)
Intervertebral disc degeneration (spinal disc degeneration)
Joint effusion (presence of extra fluid in joint covering)
Malaise (a feeling of general discomfort or uneasiness)

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Dependence
Drug hypersensitivity
Emotional distress
Hydronephrosis (water inside the kidney)
Hypersexuality
Insomnia (sleeplessness)
Joint swelling
Muscular weakness (muscle weakness)

What are the common drug interactions of Diprolene and Percocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

Foot deformity (functional disability of foot)
Impaired healing
Injection site bruising
Injection site pain
Loss of consciousness
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Procedural pain

40-49:

Cardiomegaly (increased size of heart than normal)
Hypotension (abnormally low blood pressure)
Influenza
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Fluid overload (too much fluid in the blood)
Groin pain
Heart rate increased
Multi-organ disorder (multiple organ disease)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pericardial effusion (fluid around the heart)

50-59:

Fatigue (feeling of tiredness)
Gait disturbance
Herpes zoster
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Intervertebral disc degeneration (spinal disc degeneration)
Joint effusion (presence of extra fluid in joint covering)
Lung disorder (lung disease)
Lung neoplasm (tumour of lung)

60+:

Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells)
Bone disorder
Mouth ulceration (mouth ulcers)
Oral disorder (mouth disease)
Oral pain
Osteomyelitis (infection of bone)
Palatal disorder
Palatal oedema (excessive accumulation of watery fluid in the roof of the mouth)
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Swelling

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 18 people, 31.58%
Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 13 people, 22.81%
Osteoporosis (bones weak and more likely to break): 13 people, 22.81%
Bone Density Decreased: 8 people, 14.04%
High Blood Pressure: 8 people, 14.04%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 12.28%
Indigestion: 5 people, 8.77%
Bone Loss: 5 people, 8.77%
Cardiac Failure: 5 people, 8.77%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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