Ditropan and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include calcium deficiency among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Arthrotec. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

On Jul, 15, 2026

31 people who take Ditropan and Arthrotec together, and have interactions are studied.

Ditropan and Arthrotec drug interactions.

What are the common drug interactions of Ditropan and Arthrotec, by gender? *:

female:

Calcium deficiency (lack of calcium)
Cardiac failure
Cataract (clouding of the lens inside the eye)
Cholecystitis chronic (long lasting infection of gallbladder)
Chronic kidney disease
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colostomy
Confusional state
Death unexplained
Dehydration (dryness resulting from the removal of water)

male:

Asthenia (weakness)
Balance disorder
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Memory impairment
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neck pain
Peripheral swelling
Sleep disorder
Vision blurred

What are the common drug interactions of Ditropan and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Abdominal pain upper
Acute psychosis (period of mentally unstable behaviour)
Bacteraemia (presence of bacteria in the blood)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Homicidal ideation (thoughts about human killing another human)
Hypokalaemia (low potassium)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

30-39:

Abdominal pain
Abdominal pain upper
Biliary colic
Blood bilirubin increased
Cholecystitis chronic (long lasting infection of gallbladder)
Hepatic function abnormal
Nausea post-operative (urge to vomit after surgery)
Platelet count decreased
Post-operative pain
Steatorrhoea (presence of excess fat in faeces)

40-49:

Polyuria (production of too much dilute urine)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tongue disorder (disease of tongue)
Back pain
Blood pressure increased
Cyst (a closed sac)
Dyspnoea (difficult or laboured respiration)
Genital pruritus female (itching in vagina)
Headache (pain in head)
Impaired healing

50-59:

Blood potassium decreased
Diarrhoea
Asthenia (weakness)
Chest pain
Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Extrasystoles
Fall
Malaise (a feeling of general discomfort or uneasiness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

Asthenia (weakness)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Haematocrit decreased
Intestinal perforation (complete penetration of the wall of the intestine)
Lethargy (tiredness)
Loose stools
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Nausea (feeling of having an urge to vomit)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Pain: 4 people, 12.90%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 9.68%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.45%
Irritable Bowel Syndrome: 2 people, 6.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.45%
Depression: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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