Ditropan and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Botox (botulinum toxin type a). Common drug interactions include basal cell carcinoma among females and dysgeusia among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Botox. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.



On Jul, 31, 2026

60 people who take Ditropan and Botox together, and have interactions are studied.

Ditropan and Botox drug interactions.

What are the common drug interactions of Ditropan and Botox, by gender? *:

female:

  1. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  2. Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
  3. Osteonecrosis (death of bone)
  4. Postnasal drip
  5. Vaginal haemorrhage (vaginal bleeding)
  6. Arthralgia (joint pain)
  7. Exophthalmos (bulging or protruding eyeball)
  8. Muscle spasms (muscle contraction)
  9. Back pain
  10. Blepharitis (chronic inflammation of the eyelid)

male:

  1. Dysgeusia (disorder of the sense of taste)
  2. Dyspnoea (difficult or laboured respiration)
  3. Diarrhoea
  4. Eating disorder
  5. Fatigue (feeling of tiredness)
  6. Loss of consciousness
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Rash
  9. Altered state of consciousness (altered state of mind)
  10. Blood pressure increased

What are the common drug interactions of Ditropan and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Electrocardiogram qt prolonged

20-29:

n/a

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Muscular weakness (muscle weakness)
  3. Dysarthria (speech disorder)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Asthenia (weakness)

40-49:

  1. Dehydration (dryness resulting from the removal of water)
  2. Fatigue (feeling of tiredness)
  3. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  5. Muscular weakness (muscle weakness)
  6. Procedural nausea
  7. Procedural pain
  8. Septic shock (shock due to blood infection)
  9. Complication of device insertion
  10. Asthenia (weakness)

50-59:

  1. Pain
  2. Rash
  3. Abdominal pain upper
  4. Cystitis (inflammation of the wall of the bladder)
  5. Headache (pain in head)
  6. Hospitalisation
  7. Hypotonia (low muscle tone)
  8. Mobility decreased (ability to move is reduced)
  9. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  10. Oropharyngeal pain

60+:

  1. Weight decreased
  2. Urinary tract infection
  3. Depression
  4. Escherichia infection (bacterial infection by escherichia coli)
  5. Eye disorder
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. General physical condition
  8. Haematoma (collection of blood outside the blood vessels)
  9. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  10. Impaired healing

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 21.67%
  2. Pain: 8 people, 13.33%
  3. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 8 people, 13.33%
  4. Constipation: 7 people, 11.67%
  5. Gait Disturbance: 5 people, 8.33%
  6. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 6.67%
  7. Hypersensitivity: 4 people, 6.67%
  8. Urinary Tract Infection: 4 people, 6.67%
  9. Muscle Spasms (muscle contraction): 3 people, 5.00%
  10. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ditropan and Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ditropan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ditropan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Botox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxybutynin chloride and botulinum toxin type a (the active ingredients of Ditropan and Botox, respectively), and Ditropan and Botox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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