Ditropan and Clozapine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Clozapine (clozapine). Common drug interactions include sepsis among females and granulocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Clozapine. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

On Jul, 29, 2026

74 people who take Ditropan and Clozapine together, and have interactions are studied.

Ditropan and Clozapine drug interactions.

What are the common drug interactions of Ditropan and Clozapine, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Somnolence (a state of near-sleep, a strong desire for sleep)
Vomiting
White blood cell count increased
Granulocytopenia (lack of granulocyte)
Hallucination (an experience involving the perception of something not present)
Laceration (tearing of soft body tissue)
Ligament sprain (ligament stretched)
Suicidal ideation
Abdominal distension

male:

Granulocytopenia (lack of granulocyte)
Leukopenia (less number of white blood cells in blood)
Hyperthermia (body temperature greatly above normal)
Lung neoplasm (tumour of lung)
Lymphoma (cancer that begins in immune system cells)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pneumonia
Psychiatric decompensation (worsening of symptoms to the state of a serious mental disorder)
Superinfection
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Ditropan and Clozapine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Granulocytopenia (lack of granulocyte)
White blood cell count increased

30-39:

Depression
Fall
Femur fracture
Forearm fracture (fracture in between wrist to elbow)
Gastric ulcer (stomach ulcer)
Gastritis (inflammation of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lower limb fracture
Oesophageal spasm (contraction of oesophagus)

40-49:

Granulocytopenia (lack of granulocyte)
Leukopenia (less number of white blood cells in blood)
Agitation (state of anxiety or nervous excitement)
Blood creatine phosphokinase increased
Confusional state
Hallucination, auditory (perceiving sounds without auditory stimulus)
Impulsive behaviour
Memory impairment
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Restlessness (not able to rest)

50-59:

Granulocytopenia (lack of granulocyte)
Leukopenia (less number of white blood cells in blood)
Fall
Death
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Blood albumin decreased
Blood potassium decreased
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cartilage injury
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)

60+:

Neutropenia (an abnormally low number of neutrophils)
Pneumonia
Leukopenia (less number of white blood cells in blood)
Lung neoplasm (tumour of lung)
Lymphoma (cancer that begins in immune system cells)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Psychiatric decompensation (worsening of symptoms to the state of a serious mental disorder)
Superinfection
White blood cell count decreased

What are the existing conditions these people have? *

Stress And Anxiety: 15 people, 20.27%
Depression: 12 people, 16.22%
Urination - Painful: 9 people, 12.16%
Psychotic Disorder: 6 people, 8.11%
Weight Loss: 5 people, 6.76%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 6.76%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 5 people, 6.76%
Insomnia (sleeplessness): 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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