Ditropan and Combivir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Combivir (lamivudine; zidovudine). Common drug interactions include subcutaneous abscess among females and nephritis interstitial among males.
The phase IV clinical study analyzes what interactions people have when they take Ditropan and Combivir. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Ditropan?
Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.
What is Combivir?
Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.
20 people who take Ditropan and Combivir together, and have interactions are studied.

What are the common drug interactions of Ditropan and Combivir, by gender? *:
female:
- Subcutaneous abscess
- Vomiting
- Wrist fracture
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Blood cholesterol increased
- Blood triglycerides increased
- Coma (state of unconsciousness lasting more than six hours)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diastolic dysfunction
- Neuropathy peripheral (surface nerve damage)
male:
- Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
- Renal failure acute (rapid kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Tooth fracture
- Tooth loss
- Fear of falling
- Nephrolithiasis (calculi in the kidneys)
- Physical disability
- Renal tubular necrosis (death of kidney tubules)
- Cerebral haemorrhage (bleeding within the brain)
What are the common drug interactions of Ditropan and Combivir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dizziness
- Drug ineffective
- Herpes simplex (herpes simplex is a common viral infection)
- Hypertension (high blood pressure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Insomnia (sleeplessness)
- Intervertebral disc protrusion (spinal disc protrusion)
- Loss of consciousness
- Pain in extremity
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Emotional distress
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Renal impairment (severely reduced kidney function)
- Tooth fracture
- Tooth loss
60+:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Pain in extremity
- Renal disorder (kidney disease)
- Renal failure acute (rapid kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Rib fracture
What are the existing conditions these people have? *
- Hiv Infection: 12 people, 60.00%
- Depression: 4 people, 20.00%
- Pain: 3 people, 15.00%
- Lipoatrophy (localized loss of fat tissue): 3 people, 15.00%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 15.00%
- Erection Problems: 3 people, 15.00%
- Enlarged Prostate: 3 people, 15.00%
- Sleep Disorder: 1 person, 5.00%
- Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 1 person, 5.00%
- Headache (pain in head): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Ditropan and Combivir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ditropan and Combivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ditropan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Combivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ditropan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxybutynin chloride and lamivudine; zidovudine (the active ingredients of Ditropan and Combivir, respectively), and Ditropan and Combivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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