Ditropan and Donepezil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Donepezil (donepezil hydrochloride). Common drug interactions include renal haemorrhage among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Donepezil. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

On Jul, 18, 2026

39 people who take Ditropan and Donepezil together, and have interactions are studied.

Ditropan and Donepezil drug interactions.

What are the common drug interactions of Ditropan and Donepezil, by gender? *:

female:

Renal haemorrhage (bleeding from kidney)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rhythm idioventricular (a abnormal heart rate)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Skin disorder (skin disease)
Skin haemorrhage (bleeding into skin)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Swollen tongue (swelling of tongue)

male:

Tremor (trembling or shaking movements in one or more parts of your body)
Anxiety
Acute myocardial infarction (acute heart attack)
Blood pressure decreased
Bronchial carcinoma (lung cancer)
Cardiogenic shock (inadequate circulation of blood)
Death
Electrocardiogram qrs complex prolonged
Emotional disorder
Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)

What are the common drug interactions of Ditropan and Donepezil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Anxiety
Fall
Peripheral swelling
Productive cough
Renal disorder (kidney disease)
Ventricular fibrillation (abnormally irregular heart rhythm)
Weight decreased
Abnormal behaviour
Acetabulum fracture (socket of the hip joint- fracture)
Acute myocardial infarction (acute heart attack)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 15.38%
Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 10.26%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.26%
Parkinson's Disease: 4 people, 10.26%
Bladder Disorder: 4 people, 10.26%
Hypersensitivity: 3 people, 7.69%
Sleep Disorder: 3 people, 7.69%
Pain: 3 people, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.69%
High Blood Pressure: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ditropan and Donepezil?

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