Ditropan and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Plendil (felodipine). Common drug interactions include coronary artery disease among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Plendil. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

31 people who take Ditropan and Plendil together, and have interactions are studied.

What are the common drug interactions of Ditropan and Plendil, by gender? *:

female:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery stenosis (narrowing of coronary artery)
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug ineffective
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Flushing (the warm, red condition of human skin)

male:

Back pain
Injury
Constipation
Depression
Diabetic complication
Diabetic eye disease
Fall
Gingival bleeding (bleeding gums)
Haematuria (presence of blood in urine)
Hydronephrosis (water inside the kidney)

What are the common drug interactions of Ditropan and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Back pain
Pain
Constipation
Depression
Diabetic complication
Diabetic eye disease
Fall
Gingival bleeding (bleeding gums)
Haematuria (presence of blood in urine)
Hydronephrosis (water inside the kidney)

What are the existing conditions these people have? *

Urinary Incontinence (inability to control the flow of urine and involuntary urination): 4 people, 12.90%
Multiple Myeloma (cancer of the plasma cells): 4 people, 12.90%
Memory Loss: 4 people, 12.90%
Laxative Supportive Care: 4 people, 12.90%
Indigestion: 4 people, 12.90%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 4 people, 12.90%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 12.90%
Enlarged Prostate: 4 people, 12.90%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 12.90%
Constipation: 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

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