Docetaxel and Ofev drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Docetaxel (docetaxel) and Ofev (nintedanib esylate). Common drug interactions include malignant neoplasm progression among females and idiopathic pulmonary fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Docetaxel and Ofev. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Docetaxel?

Docetaxel has active ingredients of docetaxel. eHealthMe is studying from 79,875 Docetaxel users. Check the latest studies of Docetaxel.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.

On Jul, 07, 2026

43 people who take Docetaxel and Ofev together, and have interactions are studied.

What are the common drug interactions of Docetaxel and Ofev, by gender? *:

female:

Malignant neoplasm progression (cancer tumour came back)
Neuropathy peripheral (surface nerve damage)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Nausea (feeling of having an urge to vomit)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Venous thrombosis (blood clot (thrombus) that forms within a vein)
Neutropenia (an abnormally low number of neutrophils)
Death
Idiopathic pulmonary fibrosis (chronic lung disease)

male:

Idiopathic pulmonary fibrosis (chronic lung disease)
Malignant neoplasm progression (cancer tumour came back)
Blood pressure increased
Drug intolerance (drug sensitivity)
Neutropenia (an abnormally low number of neutrophils)
Therapeutic response decreased (less preventive response)
Transaminases increased
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)

What are the common drug interactions of Docetaxel and Ofev, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Malignant neoplasm progression (cancer tumour came back)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Venous thrombosis (blood clot (thrombus) that forms within a vein)
Blood pressure increased
Transaminases increased
Disease progression

60+:

Idiopathic pulmonary fibrosis (chronic lung disease)
Neutropenia (an abnormally low number of neutrophils)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Pneumonia
Therapeutic response decreased (less preventive response)
Disease progression
Dyspnoea (difficult or laboured respiration)
Pyrexia (fever)
Haematotoxicity (toxins that destroy red blood cells)
Multi-organ disorder (multiple organ disease)

What are the existing conditions these people have? *

Lung Adenocarcinoma (a form of non-small cell lung cancer): 19 people, 44.19%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 16 people, 37.21%
Lung Neoplasm Malignant (cancer tumour of lung): 7 people, 16.28%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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