Dolobid and Novantrone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dolobid (diflunisal) and Novantrone (mitoxantrone hydrochloride). Common drug interactions include actinomycosis among females.
The phase IV clinical study analyzes what interactions people have when they take Dolobid and Novantrone. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Dolobid?
Dolobid has active ingredients of diflunisal. eHealthMe is studying from 353 Dolobid users. Check the latest studies of Dolobid.
What is Novantrone?
Novantrone has active ingredients of mitoxantrone hydrochloride. It is often used in multiple sclerosis. eHealthMe is studying from 3,349 Novantrone users. Check the latest studies of Novantrone.
11 people who take Dolobid and Novantrone together, and have interactions are studied.

What are the common drug interactions of Dolobid and Novantrone, by gender? *:
female:
- Actinomycosis (infection that causes sores, or abscesses)
- Adenoma benign (non-cancerous tumour -secreting)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Fistula (an abnormal connection or passageway between two)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gingival disorder (gum disease)
- Gingival oedema (swelling of gums)
- Hepatic steatosis (fatty liver disease)
male:
n/a
What are the common drug interactions of Dolobid and Novantrone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Apical granuloma (tumour of the apex of a nonvital tooth)
- Atelectasis (partial or complete collapse of the lung)
- Atrophic vulvovaginitis (inflammation of the vulva)
- Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
- Bone disorder
- Bone formation increased
- Bone loss
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
40-49:
- Actinomycosis (infection that causes sores, or abscesses)
- Adenoma benign (non-cancerous tumour -secreting)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Fistula (an abnormal connection or passageway between two)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gingival disorder (gum disease)
- Gingival oedema (swelling of gums)
- Hepatic steatosis (fatty liver disease)
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Stress And Anxiety: 11 people, 100.00%
- Metastases To Bone (cancer spreads to bone): 11 people, 100.00%
- Chronic Thyroiditis (long lasting inflammation of thyroid gland): 11 people, 100.00%
- Breast Cancer: 11 people, 100.00%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Dolobid and Novantrone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Dolobid (353 reports)
- Novantrone (3,349 reports)
Browse all drug interactions of Dolobid and Novantrone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dolobid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Novantrone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dolobid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Novantrone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on diflunisal and mitoxantrone hydrochloride (the active ingredients of Dolobid and Novantrone, respectively), and Dolobid and Novantrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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