Dolutegravir and Ziagen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dolutegravir (dolutegravir) and Ziagen (abacavir sulfate). Common drug interactions include pruritus among females and osteoporosis among males.

The phase IV clinical study analyzes what interactions people have when they take Dolutegravir and Ziagen. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Dolutegravir?

Dolutegravir has active ingredients of dolutegravir. eHealthMe is studying from 7,071 Dolutegravir users. Check the latest studies of Dolutegravir.

What is Ziagen?

Ziagen has active ingredients of abacavir sulfate. It is often used in hiv infection. eHealthMe is studying from 7,626 Ziagen users. Check the latest studies of Ziagen.

On Jul, 05, 2026

100 people who take Dolutegravir and Ziagen together, and have interactions are studied.

Dolutegravir and Ziagen drug interactions.

What are the common drug interactions of Dolutegravir and Ziagen, by gender? *:

female:

Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash
Renal failure (kidney dysfunction)

male:

Osteoporosis (bones weak and more likely to break)
Depressive symptom
Pain
Anxiety
Leukopenia (less number of white blood cells in blood)
Renal failure (kidney dysfunction)
Insomnia (sleeplessness)
Renal impairment (severely reduced kidney function)
Abdominal discomfort
Chronic kidney disease

What are the common drug interactions of Dolutegravir and Ziagen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Emotional distress
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pain

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Emotional distress
Pain
Hypertriglyceridaemia (excess of triglycerides in the blood)
Neuropathy peripheral (surface nerve damage)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Anxiety
Bone loss
Cerebral haemorrhage (bleeding within the brain)

50-59:

Renal impairment (severely reduced kidney function)
Osteoporosis (bones weak and more likely to break)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Multiple injuries
Nephrolithiasis (calculi in the kidneys)
Pain
Dehydration (dryness resulting from the removal of water)

60+:

Renal disorder (kidney disease)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Emotional distress
Nephropathy toxic (damage to kidney due to toxins)
Pain

What are the existing conditions these people have? *

High Blood Pressure: 22 people, 22.00%
Retinal Disorder (disease of retina): 18 people, 18.00%
Mycobacterium Avium Complex Infection: 18 people, 18.00%
Cerebral Toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii): 18 people, 18.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 17.00%
Depression: 12 people, 12.00%
Insomnia (sleeplessness): 8 people, 8.00%
Hepatitis B: 7 people, 7.00%
Depressed Mood: 7 people, 7.00%
Hypersensitivity: 6 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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