Domeboro and Zofran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Domeboro (acetic acid, glacial; aluminum acetate) and Zofran (ondansetron hydrochloride). Common drug interactions include stevens-johnson syndrome among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Domeboro and Zofran. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Domeboro?

Domeboro has active ingredients of acetic acid, glacial; aluminum acetate. eHealthMe is studying from 100 Domeboro users. Check the latest studies of Domeboro.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

12 people who take Domeboro and Zofran together, and have interactions are studied.

What are the common drug interactions of Domeboro and Zofran, by gender? *:

female:

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pleural effusion (water on the lungs)
Pneumonia
Rectal haemorrhage (bleeding from anus)
Renal failure acute (rapid kidney dysfunction)
Urinary tract infection
Anxiety

male:

Dehydration (dryness resulting from the removal of water)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Small intestinal obstruction (blockage in small intestine)
Weight decreased
Aspergillosis (an infection caused by a fungus called aspergillus)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Multi-organ failure (multisystem organ failure)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Domeboro and Zofran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aspergillosis (an infection caused by a fungus called aspergillus)
Multi-organ failure (multisystem organ failure)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pleural effusion (water on the lungs)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Skin lesion

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

60+:

Dehydration (dryness resulting from the removal of water)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urinary tract infection
Anxiety
Blood culture positive
Blood pressure diastolic decreased
Blood pressure increased
Cardiomegaly (increased size of heart than normal)
Culture urine positive

What are the existing conditions these people have? *

Pain: 5 people, 41.67%
High Blood Pressure: 4 people, 33.33%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 25.00%
Seasonal Allergy (allergic condition due to certain season): 3 people, 25.00%
Dehydration (dryness resulting from the removal of water): 3 people, 25.00%
Headache (pain in head): 2 people, 16.67%
Pneumonia: 2 people, 16.67%
Oral Cancer (mouth cancer): 2 people, 16.67%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 16.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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