Donepezil hydrochloride and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Donepezil hydrochloride (donepezil hydrochloride) and Acyclovir (acyclovir). Common drug interactions include depression among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Donepezil hydrochloride and Acyclovir. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Donepezil hydrochloride?

Donepezil hydrochloride has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 4,263 Donepezil hydrochloride users. Check the latest studies of Donepezil hydrochloride.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

On Aug, 03, 2026

27 people who take Donepezil hydrochloride and Acyclovir together, and have interactions are studied.

Donepezil hydrochloride and Acyclovir drug interactions.

What are the common drug interactions of Donepezil Hydrochloride and Acyclovir, by gender? *:

female:

Depression
Eye pain
Fatigue (feeling of tiredness)
Asthenia (weakness)
Blood glucose decreased
Decreased appetite
Drug ineffective
Eye inflammation
Eye swelling
Hallucination (an experience involving the perception of something not present)

male:

Anxiety
Diarrhoea
Liver disorder (liver diseases)
Memory impairment
Oedema (fluid collection in tissue)
Platelet count decreased
Pneumonia
Therapeutic response unexpected
Weight decreased
Aggression

What are the common drug interactions of Donepezil Hydrochloride and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Bone density decreased
Depression
Emotional distress
Fear
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain

60+:

Decreased appetite
Fatigue (feeling of tiredness)
Eye pain
Eye swelling
Fall
Hallucination (an experience involving the perception of something not present)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Joint dislocation (a joint position is changed from normal position)
Loss of consciousness
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 29.63%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 4 people, 14.81%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 14.81%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 11.11%
Delusion (a false belief or opinion): 3 people, 11.11%
Parkinson's Disease: 2 people, 7.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.41%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 7.41%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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