Donepezil and Multaq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Donepezil (donepezil hydrochloride) and Multaq (dronedarone hydrochloride). Common drug interactions include fall among females and epistaxis among males.

The phase IV clinical study analyzes what interactions people have when they take Donepezil and Multaq. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.

On Jul, 29, 2026

23 people who take Donepezil and Multaq together, and have interactions are studied.

What are the common drug interactions of Donepezil and Multaq, by gender? *:

female:

Fall
Asthenia (weakness)
Abdominal discomfort
Death
Hallucination (an experience involving the perception of something not present)
Malaise (a feeling of general discomfort or uneasiness)
Rib fracture
Spinal fracture (fracture in one of vertebrae)
Decreased appetite
Diarrhoea

male:

Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Pruritus (severe itching of the skin)
Respiratory rate decreased (less breathing rate/min)
Somnolence (a state of near-sleep, a strong desire for sleep)
Vitamin d decreased
Weight decreased
Back pain
Blood pressure decreased

What are the common drug interactions of Donepezil and Multaq, by age (0-1 to 60+)? *:

0-1:

Haemorrhage intracranial (bleeding within the skull)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Fall
Asthenia (weakness)
Decreased appetite
Diarrhoea
Parkinson's disease
Urinary tract infection
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve stenosis (narrowing of the aortic valve)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Blood pressure decreased

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 21.74%
Multiple Myeloma (cancer of the plasma cells): 5 people, 21.74%
Parkinson's Disease: 4 people, 17.39%
Atrial Thrombosis (blood clot that develops in an artery): 4 people, 17.39%
Pain: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Donepezil and Multaq?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously