Doxorubicin hydrochloride and Zyprexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxorubicin hydrochloride (doxorubicin hydrochloride) and Zyprexa (olanzapine). Common drug interactions include headache among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Doxorubicin hydrochloride and Zyprexa. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Doxorubicin hydrochloride?

Doxorubicin hydrochloride has active ingredients of doxorubicin hydrochloride. eHealthMe is studying from 25,343 Doxorubicin hydrochloride users. Check the latest studies of Doxorubicin hydrochloride.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

On Jul, 18, 2026

18 people who take Doxorubicin hydrochloride and Zyprexa together, and have interactions are studied.

Doxorubicin hydrochloride and Zyprexa drug interactions.

What are the common drug interactions of Doxorubicin Hydrochloride and Zyprexa, by gender? *:

female:

Headache (pain in head)
Myalgia (muscle pain)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Abscess neck (neck abscesses)
Blood triglycerides increased
Confusional state
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Incoherent (talking in a confused and unclear way)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)

male:

Febrile neutropenia (fever with reduced white blood cells)
Interstitial lung disease
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oral candidiasis (fungal infection of mouth)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)

What are the common drug interactions of Doxorubicin Hydrochloride and Zyprexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Febrile neutropenia (fever with reduced white blood cells)

10-19:

n/a

20-29:

n/a

30-39:

Oral candidiasis (fungal infection of mouth)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)

40-49:

Drug ineffective
Headache (pain in head)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Vomiting

50-59:

Abscess neck (neck abscesses)
Blood triglycerides increased
Confusional state
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Incoherent (talking in a confused and unclear way)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Pneumonia
Restlessness (not able to rest)

60+:

Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Infusion related reaction
Interstitial lung disease
Lymphoma (cancer that begins in immune system cells)
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Red blood cell count decreased
Splenic haemorrhage (bleeding from spleen)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 4 people, 22.22%
Abdominal Pain Upper: 3 people, 16.67%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 3 people, 16.67%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 16.67%
High Blood Pressure: 1 person, 5.56%
Breast Cancer: 1 person, 5.56%
Constipation: 1 person, 5.56%
Cough: 1 person, 5.56%
Depression: 1 person, 5.56%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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