Doxycycline and Amisulpride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Amisulpride (amisulpride). Common drug interactions include hepatic failure among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Amisulpride. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Amisulpride?

Amisulpride has active ingredients of amisulpride. eHealthMe is studying from 6,389 Amisulpride users. Check the latest studies of Amisulpride.



On Aug, 06, 2026

18 people who take Doxycycline and Amisulpride together, and have interactions are studied.

Doxycycline and Amisulpride drug interactions.

What are the common drug interactions of Doxycycline and Amisulpride, by gender? *:

female:

  1. Hepatic failure (liver failure)
  2. Asthenia (weakness)
  3. Abdominal distension
  4. Abdominal pain
  5. Anaemia (lack of blood)
  6. Arthralgia (joint pain)
  7. Decreased appetite
  8. Diarrhoea
  9. Hepatosplenomegaly (enlargement of both the liver and the spleen)
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  3. Respiratory tract infection
  4. Schizophrenia, disorganised type (speech and behaviour that are disorganized or difficult to understand)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Dementia (madness)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Doxycycline and Amisulpride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hepatic failure (liver failure)
  2. Liver transplant
  3. Asthenia (weakness)
  4. Depression
  5. Hot flush (sudden feelings of heat)
  6. Insomnia (sleeplessness)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Vertigo

50-59:

  1. Agitation (state of anxiety or nervous excitement)
  2. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Dementia (madness)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. General physical health deterioration (weak health status)
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

60+:

  1. Abdominal distension
  2. Abdominal pain
  3. Hypotension (abnormally low blood pressure)
  4. Infarction (obstruction of the blood supply to an organ or region of tissue)
  5. Inflammatory marker increased
  6. Joint stiffness
  7. Oedema peripheral (superficial swelling)
  8. Pallor
  9. Pleural effusion (water on the lungs)
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 13 people, 72.22%
  2. Pain: 11 people, 61.11%
  3. Dyslipidaemia (abnormal amount of lipids): 4 people, 22.22%
  4. Depression: 4 people, 22.22%
  5. Whipple's Disease (infection with a bacteria called tropheryma whippelii): 2 people, 11.11%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Doxycycline and Amisulpride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amisulpride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxycycline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amisulpride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate and amisulpride (the active ingredients of Doxycycline and Amisulpride, respectively), and Doxycycline and Amisulpride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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