Doxycycline and Claravis drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Claravis (isotretinoin). Common drug interactions include anxiety among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Claravis. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Doxycycline?
Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.
What is Claravis?
Claravis has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,636 Claravis users. Check the latest studies of Claravis.
39 people who take Doxycycline and Claravis together, and have interactions are studied.

What are the common drug interactions of Doxycycline and Claravis, by gender? *:
female:
- Anxiety
- Asthma exercise induced
- Diplopia (double vision)
- Headache (pain in head)
- Hospitalisation
- Ligament sprain (ligament stretched)
- Nasal polyps (masses that develop in the lining of the nose)
- Suicidal ideation
- Surgery
- Upper respiratory tract infection
male:
- Anxiety
- Depression
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cartilage injury
- Femoroacetabular impingement (a condition affecting the hip joint in young and middle-aged adults)
- Joint stiffness
- Nephropathy (damage to or disease of a kidney)
- Osteonecrosis (death of bone)
- Renal injury (kidney injury)
- Skeletal injury (bone and supporting muscle injury)
What are the common drug interactions of Doxycycline and Claravis, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Suicidal ideation
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Anxiety
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cystic fibrosis related diabetes
- Depression
- Ear disorder
- Eye irritation
20-29:
- Diplopia (double vision)
- Headache (pain in head)
- Anxiety
- Crying
- Decreased appetite
- Hospitalisation
- Insomnia (sleeplessness)
- Suicidal ideation
30-39:
- Bone density decreased
- Bone disorder
- Bone loss
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cartilage injury
- Femoroacetabular impingement (a condition affecting the hip joint in young and middle-aged adults)
- Joint stiffness
- Nephropathy (damage to or disease of a kidney)
- Osteonecrosis (death of bone)
- Renal injury (kidney injury)
40-49:
- Back disorder
- Bedridden
- Cellulitis (infection under the skin)
- Pruritus (severe itching of the skin)
- Wrist fracture
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 20.51%
- Immunodeficiency Common Variable: 6 people, 15.38%
- Acne Cystic (skin problems that cause pimples): 6 people, 15.38%
- Hidradenitis (chronic disease of a type of sweat gland): 4 people, 10.26%
- Hiv Infection: 2 people, 5.13%
- Cystic Fibrosis (disease of the secretary glands): 2 people, 5.13%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.13%
* Approximation only. Some reports may have incomplete information.
Do you take Doxycycline and Claravis?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Doxycycline (60,868 reports)
- Claravis (9,636 reports)
Browse all drug interactions of Doxycycline and Claravis:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Doxycycline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Claravis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Doxycycline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Claravis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on doxycycline hyclate and isotretinoin (the active ingredients of Doxycycline and Claravis, respectively), and Doxycycline and Claravis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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