Doxycycline and Factive drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Factive (gemifloxacin mesylate). Common drug interactions include abdominal pain lower among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Factive. It is created by eHealthMe based on reports of 10 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

What is Factive?

Factive has active ingredients of gemifloxacin mesylate. eHealthMe is studying from 1,430 Factive users. Check the latest studies of Factive.

On Jul, 21, 2026

10 people who take Doxycycline and Factive together, and have interactions are studied.

Doxycycline and Factive drug interactions.

What are the common drug interactions of Doxycycline and Factive, by gender? *:

female:

Abdominal pain lower
Anxiety
Arteritis (inflammation of the walls of arteries)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Arthropathy
Bone loss
Bone pain
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Drug hypersensitivity

male:

Hypotension (abnormally low blood pressure)
Pulmonary oedema (fluid accumulation in the lungs)
Anisocytosis (patient's red blood cells are of unequal size)
Anti-hbc igm antibody positive
Anxiety
Aortic calcification (aortic calcification sign of heart valve disease)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve incompetence
Ascites (accumulation of fluid in the abdominal cavity)
Asterixis (flapping tremor, or liver flap)

What are the common drug interactions of Doxycycline and Factive, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Rash

30-39:

Anti-hbc igm antibody positive
Asterixis (flapping tremor, or liver flap)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood albumin decreased
Blood calcium decreased
Blood chloride decreased
Blood lactate dehydrogenase increased
Blood pressure systolic increased
Blood sodium decreased
Bone marrow disorder

40-49:

Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Emotional distress
Gallbladder disorder
Injury
Pain

50-59:

n/a

60+:

Alcohol abuse
Amaurosis fugax (painless transient monocular visual loss)
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure congestive
Cardioactive drug level above therapeutic
Carotid arteriosclerosis (plaque deposition in artery)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Respiratory Tract Infection Bacterial: 3 people, 30.00%
Urinary Tract Infection: 1 person, 10.00%
Sinusitis (inflammation of sinus): 1 person, 10.00%
Pneumonia: 1 person, 10.00%
Pain: 1 person, 10.00%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 10.00%
Joint Pain: 1 person, 10.00%
Genital Rash (rash on sex organ): 1 person, 10.00%
Fever: 1 person, 10.00%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

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