Doxycycline and Monodox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Monodox (doxycycline). Common drug interactions include corneal graft rejection among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Monodox. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Monodox?

Monodox has active ingredients of doxycycline. It is often used in acne. eHealthMe is studying from 388 Monodox users. Check the latest studies of Monodox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

20 people who take Doxycycline and Monodox together, and have interactions are studied.

Doxycycline and Monodox drug interactions.

What are the common drug interactions of Doxycycline and Monodox, by gender? *:

female:

Corneal graft rejection
Eye infection
Eye swelling
Ocular hyperaemia (an abnormally large amount of blood in eye)
Anxiety
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression

male:

Pneumonia
Diarrhoea
Paranasal sinus hypersecretion
Respiratory tract infection
Sinus node dysfunction (a group of abnormal heart rhythms)
Sleep disorder
Troponin increased
Abdominal discomfort
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood glucose increased

What are the common drug interactions of Doxycycline and Monodox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Oedema peripheral (superficial swelling)
Pain
Pain in extremity
Post thrombotic syndrome (long-term effects that can occur after venous thrombosis)
Anal fissure
Back pain

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea

50-59:

Pneumonia

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Corneal graft rejection
Hypotension (abnormally low blood pressure)
Left ventricular failure (left ventricle fails to contract forcefully)
Nausea (feeling of having an urge to vomit)
Pneumonia
Sinus node dysfunction (a group of abnormal heart rhythms)
Transaminases increased
Troponin increased
Urinary tract infection

What are the existing conditions these people have? *

Rosacea (a skin condition that causes facial redness): 4 people, 20.00%
Stress And Anxiety: 4 people, 20.00%
Pneumonia: 3 people, 15.00%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 10.00%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 10.00%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 10.00%
Hypokalemia (low potassium): 2 people, 10.00%
Hypersensitivity: 2 people, 10.00%
Enlarged Prostate: 2 people, 10.00%
Depression: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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