Doxycycline and Mycelex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Mycelex (clotrimazole). Common drug interactions include glossodynia among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Mycelex. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

What is Mycelex?

Mycelex has active ingredients of clotrimazole. eHealthMe is studying from 1,876 Mycelex users. Check the latest studies of Mycelex.



On Jul, 16, 2026

38 people who take Doxycycline and Mycelex together, and have interactions are studied.

Doxycycline and Mycelex drug interactions.

What are the common drug interactions of Doxycycline and Mycelex, by gender? *:

female:

  1. Glossodynia (a burning or painful sensation in the tongue)
  2. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  3. Hypersensitivity
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  5. Jejunitis (inflammation of the jejunum of the small intestine)
  6. Joint swelling
  7. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  8. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Obesity (having too much body fat)

male:

  1. Dehydration (dryness resulting from the removal of water)
  2. Vomiting
  3. Oesophagitis (inflammation of oesophagus)
  4. Splenomegaly (enlargement of spleen)
  5. Nausea (feeling of having an urge to vomit)
  6. Abdominal pain upper
  7. Bezoar (mass found trapped in the gastrointestinal system)
  8. Thrombocytopenia (decrease of platelets in blood)
  9. Blood bilirubin increased
  10. Blood bilirubin unconjugated increased

What are the common drug interactions of Doxycycline and Mycelex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Chest pain
  2. Dehydration (dryness resulting from the removal of water)
  3. Dyspnoea (difficult or laboured respiration)
  4. Hydronephrosis (water inside the kidney)
  5. Vomiting
  6. Abdominal pain
  7. Blood albumin decreased
  8. Diarrhoea
  9. Hepatosplenomegaly (enlargement of both the liver and the spleen)
  10. Oesophageal ulcer (ulcer of oesophagus)

30-39:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Asthma
  4. Back pain
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Chest discomfort
  7. Chest pain
  8. Cholecystitis (infection of gallbladder)
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

40-49:

  1. Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
  2. Anaemia (lack of blood)
  3. Blood osmolarity decreased
  4. Cachexia (loss of weight)
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Death
  7. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  8. Dehydration (dryness resulting from the removal of water)
  9. Encephalopathy (functioning of the brain is affected by some agent or condition)
  10. Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)

50-59:

  1. Oral candidiasis (fungal infection of mouth)
  2. Spinal osteoarthritis (joint cartilage loss in spine)
  3. Urethral stenosis (narrowing of the urethra, may cause decreased urine output)
  4. Abdominal pain
  5. Acute sinusitis
  6. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  7. Allergic colitis (inflammation of the colon due to allergy)
  8. Alopecia (absence of hair from areas of the body)
  9. Anaemia (lack of blood)
  10. Aneurysm (enlargement of an artery caused by a weakening of the artery wall)

60+:

  1. Pneumonia
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Neck pain
  4. Pain
  5. Plasma cell myeloma (cancer that begins in plasma cells)
  6. Rash macular (small, flat red spots)
  7. Toothache (tooth pain)
  8. Abasia (inability to walk)
  9. Abdominal pain
  10. Acute pulmonary oedema (sudden deposit of fluid in the lung))

What are the existing conditions these people have? *

  1. Depression: 10 people, 26.32%
  2. Nausea (feeling of having an urge to vomit): 8 people, 21.05%
  3. High Blood Pressure: 7 people, 18.42%
  4. Infection: 7 people, 18.42%
  5. Pain: 7 people, 18.42%
  6. Nausea And Vomiting: 6 people, 15.79%
  7. Diabetes: 6 people, 15.79%
  8. Type 2 Diabetes: 6 people, 15.79%
  9. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 6 people, 15.79%
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 15.79%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Doxycycline and Mycelex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mycelex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxycycline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mycelex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate and clotrimazole (the active ingredients of Doxycycline and Mycelex, respectively), and Doxycycline and Mycelex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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