Doxycycline and Panadol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Panadol (acetaminophen). Common drug interactions include chronic kidney disease among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Panadol. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Panadol?

Panadol has active ingredients of acetaminophen. eHealthMe is studying from 607 Panadol users. Check the latest studies of Panadol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11 people who take Doxycycline and Panadol together, and have interactions are studied.

Doxycycline and Panadol drug interactions.

What are the common drug interactions of Doxycycline and Panadol, by gender? *:

female:

Chronic kidney disease
Asthenia (weakness)
Asthma
Bradycardia (abnormally slow heart action)
Cough
Dyspnoea (difficult or laboured respiration)
Nasopharyngitis (inflammation of the nasopharynx)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Superior vena cava syndrome (obstruction of blood flow through the superior vena cava)
Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)

male:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pyrexia (fever)
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)
Arthralgia (joint pain)
Lower respiratory tract infection
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Biliary sepsis
Iridocyclitis (inflammation of the iris and ciliary body of the eye)

What are the common drug interactions of Doxycycline and Panadol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Superior vena cava syndrome (obstruction of blood flow through the superior vena cava)
Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)

40-49:

n/a

50-59:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pyrexia (fever)

60+:

Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Chronic kidney disease
Lower respiratory tract infection
Malignant neoplasm progression (cancer tumour came back)
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia
Renal impairment (severely reduced kidney function)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sepsis (a severe blood infection that can lead to organ failure and death)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)

What are the existing conditions these people have? *

Back Pain: 4 people, 36.36%
Constipation: 4 people, 36.36%
Rashes (redness): 4 people, 36.36%
Multiple Myeloma (cancer of the plasma cells): 4 people, 36.36%
Abdominal Pain: 3 people, 27.27%
Pain: 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Neuralgia (pain in one or more nerves): 3 people, 27.27%
Insomnia (sleeplessness): 3 people, 27.27%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

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