Doxycycline and Plegridy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Plegridy (peginterferon beta-1a). Common drug interactions include paraesthesia among females and burning sensation among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Plegridy. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

On Jul, 26, 2026

14 people who take Doxycycline and Plegridy together, and have interactions are studied.

Doxycycline and Plegridy drug interactions.

What are the common drug interactions of Doxycycline and Plegridy, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Gait disturbance
Blood magnesium decreased
Blood potassium decreased
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Cellulitis (infection under the skin)
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Fall
Feeling hot

male:

Burning sensation
Dry skin
Pruritus (severe itching of the skin)
Epididymitis (pain in the scrotum or testicle)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hypersensitivity
Injection site bruising
Injection site reaction
Nightmare (unpleasant dream)

What are the common drug interactions of Doxycycline and Plegridy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Burning sensation
Dry skin
Epididymitis (pain in the scrotum or testicle)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hypersensitivity
Injection site bruising
Injection site reaction
Nightmare (unpleasant dream)
Pain

40-49:

Gait disturbance
Injection site bruising

50-59:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Blood magnesium decreased
Heart rate increased
Hypoaesthesia (reduced sense of touch or sensation)
Injection site erythema (redness at injection site)
Injection site mass
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Palpitations (feelings or sensations that your heart is pounding or racing)
Rash
Rash papular (redness with papule)

60+:

n/a

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 78.57%
Stress And Anxiety: 1 person, 7.14%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.14%
Epididymitis (pain in the scrotum or testicle): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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