Dramamine and Hydroxyzine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dramamine (dimenhydrinate) and Hydroxyzine hydrochloride (hydroxyzine hydrochloride). Common drug interactions include headache among females.

The phase IV clinical study analyzes what interactions people have when they take Dramamine and Hydroxyzine hydrochloride. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Dramamine?

Dramamine has active ingredients of dimenhydrinate. It is often used in motion sickness. eHealthMe is studying from 1,386 Dramamine users. Check the latest studies of Dramamine.

What is Hydroxyzine hydrochloride?

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 10,486 Hydroxyzine hydrochloride users. Check the latest studies of Hydroxyzine hydrochloride.



On Jul, 19, 2026

12 people who take Dramamine and Hydroxyzine hydrochloride together, and have interactions are studied.

Dramamine and Hydroxyzine hydrochloride drug interactions.

What are the common drug interactions of Dramamine and Hydroxyzine Hydrochloride, by gender? *:

female:

  1. Headache (pain in head)
  2. Dyspnoea (difficult or laboured respiration)
  3. Respiratory tract infection
  4. Sinusitis (inflammation of sinus)
  5. Viral infection
  6. Vomiting
  7. Weight decreased
  8. Bacterial infection
  9. Chest discomfort
  10. Hypoxia (low oxygen in tissues)

male:

n/a

What are the common drug interactions of Dramamine and Hydroxyzine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Death

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Respiratory tract infection
  4. Sinusitis (inflammation of sinus)
  5. Viral infection
  6. Vomiting
  7. Weight decreased
  8. Bacterial infection
  9. Chest discomfort
  10. Hypoxia (low oxygen in tissues)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 5 people, 41.67%
  2. High Blood Pressure: 4 people, 33.33%
  3. Indigestion: 3 people, 25.00%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 25.00%
  5. Dyslipidaemia (abnormal amount of lipids): 3 people, 25.00%
  6. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 25.00%
  7. Rickets (softening of bones): 3 people, 25.00%
  8. Insomnia (sleeplessness): 3 people, 25.00%
  9. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
  10. Neck Pain: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Dramamine and Hydroxyzine hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dramamine and Hydroxyzine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dramamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyzine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dramamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dimenhydrinate and hydroxyzine hydrochloride (the active ingredients of Dramamine and Hydroxyzine hydrochloride, respectively), and Dramamine and Hydroxyzine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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