Dramamine and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dramamine (dimenhydrinate) and Premarin (estrogens, conjugated). Common drug interactions include renal failure among females.

The phase IV clinical study analyzes what interactions people have when they take Dramamine and Premarin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Dramamine?

Dramamine has active ingredients of dimenhydrinate. It is often used in motion sickness. eHealthMe is studying from 1,386 Dramamine users. Check the latest studies of Dramamine.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.



On Jul, 13, 2026

16 people who take Dramamine and Premarin together, and have interactions are studied.

Dramamine and Premarin drug interactions.

What are the common drug interactions of Dramamine and Premarin, by gender? *:

female:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
  4. Arrhythmia (irregular heartbeat)
  5. Asthenia (weakness)
  6. Blood cholesterol increased
  7. Cardiac arrest
  8. Cardiac disorder
  9. Cardiac failure congestive
  10. Cerebral infarction (less blood supply to brain resulting tissue damage)

male:

n/a

What are the common drug interactions of Dramamine and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Osteoporosis (bones weak and more likely to break)

50-59:

  1. Oropharyngeal blistering (blister of oropharynx)

60+:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Depression
  6. Dyspnoea (difficult or laboured respiration)
  7. Electrocardiogram abnormal
  8. Electrocardiogram qt prolonged
  9. Eye disorder
  10. Eye infection

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 4 people, 25.00%
  2. Blood Pressure Abnormal: 4 people, 25.00%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 12.50%
  6. Eye Disorder: 2 people, 12.50%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.25%
  8. Blood Pressure Systolic Increased: 1 person, 6.25%
  9. Breakthrough Pain: 1 person, 6.25%
  10. Cardiac Disorder: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Dramamine and Premarin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dramamine and Premarin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dramamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Premarin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dramamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Premarin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dimenhydrinate and estrogens, conjugated (the active ingredients of Dramamine and Premarin, respectively), and Dramamine and Premarin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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