Drisdol and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Drisdol (ergocalciferol) and Ambien (zolpidem tartrate). Common drug interactions include hypotension among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Drisdol and Ambien. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.



On Jul, 13, 2026

94 people who take Drisdol and Ambien together, and have interactions are studied.

Drisdol and Ambien drug interactions.

What are the common drug interactions of Drisdol and Ambien, by gender? *:

female:

  1. Hypotension (abnormally low blood pressure)
  2. Vomiting
  3. Chronic kidney disease
  4. Anxiety
  5. Blood cholesterol increased
  6. Blood pressure decreased
  7. Dehydration (dryness resulting from the removal of water)
  8. Diarrhoea
  9. Hypertension (high blood pressure)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Pneumonia
  2. Fall
  3. Nausea (feeling of having an urge to vomit)
  4. Prostatic disorder
  5. Upper respiratory tract infection
  6. Influenza
  7. Abdominal pain
  8. Asthenia (weakness)
  9. Bone disorder
  10. Bone formation increased

What are the common drug interactions of Drisdol and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Influenza
  2. Weight decreased

30-39:

  1. Pain
  2. Anxiety
  3. Emotional distress
  4. Pericardial effusion (fluid around the heart)
  5. Pericarditis (inflammation of the pericardium)
  6. Peroneal nerve palsy
  7. Pleuritic pain
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Pulmonary oedema (fluid accumulation in the lungs)
  10. Back pain

40-49:

  1. Anxiety
  2. Chronic kidney disease
  3. Muscle spasms (muscle contraction)
  4. Pain
  5. Renal failure acute (rapid kidney dysfunction)
  6. Surgery
  7. Abasia (inability to walk)
  8. Abdominal pain
  9. Activities of daily living impaired
  10. Acute myocardial infarction (acute heart attack)

50-59:

  1. Muscular weakness (muscle weakness)
  2. Papillary thyroid cancer
  3. Sinusitis (inflammation of sinus)
  4. Chronic kidney disease
  5. Renal failure (kidney dysfunction)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Alopecia (absence of hair from areas of the body)
  8. Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
  9. Breast cancer
  10. Coagulopathy (blood's ability to clot is impaired)

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Hypotension (abnormally low blood pressure)
  3. White blood cell count decreased
  4. Blood pressure decreased
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Hypertension (high blood pressure)
  7. Nausea (feeling of having an urge to vomit)
  8. Prostatic disorder
  9. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  10. Upper respiratory tract infection

What are the existing conditions these people have? *

  1. Depression: 19 people, 20.21%
  2. Pain: 18 people, 19.15%
  3. Stress And Anxiety: 15 people, 15.96%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 14.89%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 14.89%
  6. High Blood Pressure: 13 people, 13.83%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 11.70%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.64%
  9. Nausea (feeling of having an urge to vomit): 10 people, 10.64%
  10. Sleep Disorder: 8 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Drisdol and Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambien and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and zolpidem tartrate (the active ingredients of Drisdol and Ambien, respectively), and Drisdol and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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