Drisdol and Guaifenesin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Drisdol (ergocalciferol) and Guaifenesin (guaifenesin). Common drug interactions include tachypnoea among females and influenza among males.

The phase IV clinical study analyzes what interactions people have when they take Drisdol and Guaifenesin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.



On Jul, 12, 2026

36 people who take Drisdol and Guaifenesin together, and have interactions are studied.

Drisdol and Guaifenesin drug interactions.

What are the common drug interactions of Drisdol and Guaifenesin, by gender? *:

female:

  1. Tachypnoea (a condition of rapid breathing over 20 per minute)
  2. Thrombocytosis
  3. Viral infection
  4. Weight increased
  5. White blood cell count increased
  6. Anxiety
  7. Depression
  8. Left ventricular failure (left ventricle fails to contract forcefully)
  9. Pulmonary congestion (congestion in the lungs)
  10. Scapula fracture (a fracture of the scapula, the shoulder blade)

male:

  1. Influenza
  2. Pneumonia
  3. Death
  4. Dyspnoea (difficult or laboured respiration)
  5. Enteritis (inflammation of the small intestine)
  6. Fluid retention (an abnormal accumulation of fluid in the blood)
  7. Foot fracture
  8. Hypotension (abnormally low blood pressure)
  9. Ileus (a painful obstruction of the ileum or other part of the intestine)
  10. Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)

What are the common drug interactions of Drisdol and Guaifenesin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Influenza
  2. Pneumonia
  3. Respiratory distress (difficulty in breathing)
  4. Alanine aminotransferase increased
  5. Aspartate aminotransferase increased
  6. Blood alkaline phosphatase increased
  7. Blood calcium decreased
  8. Enteritis (inflammation of the small intestine)
  9. Foot fracture
  10. Hypotension (abnormally low blood pressure)

20-29:

  1. Anxiety
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Chronic kidney disease
  4. Crying
  5. Depression
  6. Emotional distress
  7. Pain
  8. Renal atrophy (wasting of kidney)
  9. Renal impairment (severely reduced kidney function)
  10. Restlessness (not able to rest)

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

50-59:

  1. Blood potassium decreased
  2. Blood sodium decreased
  3. Blood uric acid increased
  4. Brain natriuretic peptide increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Chest discomfort
  7. Chest pain
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Constipation
  10. Dehydration (dryness resulting from the removal of water)

60+:

  1. Diarrhoea
  2. Dyspnoea (difficult or laboured respiration)
  3. Wheezing (a high-pitched whistling sound made while you breath)
  4. Abdominal distension
  5. Acute sinusitis
  6. Atelectasis (partial or complete collapse of the lung)
  7. Brain natriuretic peptide increased
  8. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  9. Colitis (inflammation of colon)
  10. Deafness

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 19.44%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 19.44%
  3. Sleep Disorder: 4 people, 11.11%
  4. Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 11.11%
  5. Bone Density Decreased: 4 people, 11.11%
  6. Bronchial Hyperreactivity: 4 people, 11.11%
  7. Constipation: 4 people, 11.11%
  8. Depression: 4 people, 11.11%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 11.11%
  10. Muscle Spasms (muscle contraction): 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Drisdol and Guaifenesin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Drisdol and Guaifenesin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Guaifenesin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Guaifenesin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and guaifenesin (the active ingredients of Drisdol and Guaifenesin, respectively), and Drisdol and Guaifenesin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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