Drisdol and Humira drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Drisdol (ergocalciferol) and Humira (adalimumab). Common drug interactions include chest pain among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Drisdol and Humira. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.



On Jul, 19, 2026

49 people who take Drisdol and Humira together, and have interactions are studied.

Drisdol and Humira drug interactions.

What are the common drug interactions of Drisdol and Humira, by gender? *:

female:

  1. Chest pain
  2. Confusional state
  3. Dizziness
  4. Drug intolerance (drug sensitivity)
  5. Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
  6. Facet joint syndrome (problem with movement of the facet joints of the spine)
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. General physical health deterioration (weak health status)
  9. Hepatic enzyme increased
  10. Hip arthroplasty

male:

  1. Cardiac disorder
  2. Skin lesion
  3. Rash papular (redness with papule)
  4. Blood glucose decreased
  5. Foot deformity (functional disability of foot)
  6. Hidradenitis (chronic disease of a type of sweat gland)
  7. Nephrolithiasis (calculi in the kidneys)
  8. Pain
  9. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  10. Soft tissue neoplasm (tumour of soft tissue)

What are the common drug interactions of Drisdol and Humira, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Depression

20-29:

  1. Abdominal pain upper
  2. Migraine (headache)
  3. Sinusitis (inflammation of sinus)
  4. Swelling
  5. Synovial rupture (tear of synovial membrane of joint)
  6. Vomiting
  7. Application site vesicles (small bubble within a cell at application site)
  8. Disease progression
  9. Joint stiffness
  10. Nausea (feeling of having an urge to vomit)

30-39:

  1. Fatigue (feeling of tiredness)
  2. Injection site pain
  3. Acidosis (build-up of carbon dioxide in the blood)
  4. Asthma
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Dehydration (dryness resulting from the removal of water)
  7. Diarrhoea
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Ear pain
  10. Hypersensitivity

40-49:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  3. Insomnia (sleeplessness)
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Myalgia (muscle pain)
  6. Oedema (fluid collection in tissue)
  7. Oedema peripheral (superficial swelling)
  8. Pain
  9. Vomiting
  10. Back pain

50-59:

  1. Arthralgia (joint pain)
  2. Bone pain
  3. Eye pain
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Herpes zoster
  7. Pain
  8. Depressed level of consciousness
  9. Foot fracture
  10. Intestinal obstruction

60+:

  1. Pain in extremity
  2. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  3. Peripheral vascular disorder
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Fibromyalgia (a long-term condition which causes pain all over the body)
  6. Injury
  7. Weight decreased
  8. Foot deformity (functional disability of foot)
  9. Foreign body in eye (foreign particle in eye)
  10. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 20.41%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 16.33%
  3. Depression: 7 people, 14.29%
  4. High Blood Cholesterol: 7 people, 14.29%
  5. Asthma: 6 people, 12.24%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 10.20%
  7. Cough: 5 people, 10.20%
  8. Stress And Anxiety: 5 people, 10.20%
  9. Pain: 5 people, 10.20%
  10. Psoriasis (immune-mediated disease that affects the skin): 5 people, 10.20%

* Approximation only. Some reports may have incomplete information.

Do you take Drisdol and Humira?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Drisdol and Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Humira and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and adalimumab (the active ingredients of Drisdol and Humira, respectively), and Drisdol and Humira (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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