Drisdol and Tessalon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Drisdol (ergocalciferol) and Tessalon (benzonatate). Common drug interactions include loss of consciousness among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Drisdol and Tessalon. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.

What is Tessalon?

Tessalon has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 6,493 Tessalon users. Check the latest studies of Tessalon.



On Jul, 29, 2026

30 people who take Drisdol and Tessalon together, and have interactions are studied.

Drisdol and Tessalon drug interactions.

What are the common drug interactions of Drisdol and Tessalon, by gender? *:

female:

  1. Loss of consciousness
  2. Lymphadenopathy (disease or enlargement of lymph nodes)
  3. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  4. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  5. Micturition urgency (urgency to pass the urine)
  6. Migraine (headache)
  7. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  8. Multiple injuries
  9. Muscle spasms (muscle contraction)
  10. Muscle tightness

male:

  1. Hypotension (abnormally low blood pressure)
  2. Pneumonia
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Acute myocardial infarction (acute heart attack)
  5. Bone density decreased
  6. Bone loss
  7. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  8. Cardiac disorder
  9. Dizziness
  10. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)

What are the common drug interactions of Drisdol and Tessalon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Osteonecrosis (death of bone)
  5. Pain
  6. Bone density decreased
  7. Bone loss
  8. Generalised oedema (swelling all over the body)
  9. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
  10. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

  1. Frostbite (damage is caused to skin and other tissues due to freezing)
  2. Loss of consciousness
  3. Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

  1. Carcinoid tumour pulmonary (slow growing tumour)
  2. Dyslipidaemia (abnormal amount of lipids)
  3. Dyspnoea (difficult or laboured respiration)
  4. Hypertension (high blood pressure)
  5. Hypertriglyceridaemia (excess of triglycerides in the blood)
  6. Lung neoplasm malignant (cancer tumour of lung)
  7. Obesity (having too much body fat)
  8. Renal failure (kidney dysfunction)
  9. Cardiac disorder
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

  1. Peripheral swelling
  2. Cellulitis (infection under the skin)
  3. Pneumonia
  4. Abdominal distension
  5. Arthralgia (joint pain)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Infusion related reaction
  10. Injury

What are the existing conditions these people have? *

  1. Stress And Anxiety: 6 people, 20.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 20.00%
  3. Pain: 5 people, 16.67%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 16.67%
  5. Itching: 5 people, 16.67%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.67%
  7. Asthma: 5 people, 16.67%
  8. Nausea (feeling of having an urge to vomit): 4 people, 13.33%
  9. Multiple Myeloma (cancer of the plasma cells): 4 people, 13.33%
  10. High Blood Pressure: 4 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Drisdol and Tessalon?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Drisdol and Tessalon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tessalon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tessalon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and benzonatate (the active ingredients of Drisdol and Tessalon, respectively), and Drisdol and Tessalon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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