Duac and Tylenol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duac (benzoyl peroxide; clindamycin phosphate) and Tylenol (acetaminophen). Common drug interactions include brain hypoxia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Duac and Tylenol. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Duac?

Duac has active ingredients of benzoyl peroxide; clindamycin phosphate. It is often used in acne. eHealthMe is studying from 745 Duac users. Check the latest studies of Duac.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.

On Jul, 27, 2026

14 people who take Duac and Tylenol together, and have interactions are studied.

What are the common drug interactions of Duac and Tylenol, by gender? *:

female:

Brain hypoxia (reduced supply of oxygen to the brain)
Brain injury
Cardiac arrest
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cerebral thrombosis (blood clot in brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Emotional distress

male:

Anxiety
Confusional state
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dehydration (dryness resulting from the removal of water)
Depression
Disturbance in attention
Fall

What are the common drug interactions of Duac and Tylenol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abnormal faeces (abnormal stool)
Autoimmune hepatitis
Back pain
Bowel movement irregularity
Cough
Decreased appetite
Dry throat
Ear infection
Ear pain
Folliculitis (infection of hair root)

20-29:

Mobility decreased (ability to move is reduced)
Psychological trauma
Pulmonary embolism (blockage of the main artery of the lung)
Pulse absent
Pupillary reflex impaired
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Swelling
Tenderness (pain or discomfort when an affected area is touched)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Unresponsive to stimuli

30-39:

n/a

40-49:

Anxiety
Aspartate aminotransferase increased
Blood pressure increased
Confusional state
Disturbance in attention
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hyperhidrosis (abnormally increased sweating)
Hypermetabolism (abnormal increase in the body's basal metabolic rate)
Night sweats (sweating in night)
Petit mal epilepsy (absence seizure)

50-59:

Asthenia (weakness)
Febrile neutropenia (fever with reduced white blood cells)
Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
Anaemia (lack of blood)
Anxiety
Blood cholesterol increased
Cardiac arrest
Cardiomyopathy (weakening of the heart muscle)
Carotid artery occlusion (artery blockage)
Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)

60+:

Abdominal pain
Adverse drug reaction
Haematochezia (passage of stools containing blood)
Injection site bruising
Irritability
Mechanical urticaria (urticaria is triggered by mechanical shearing forces e.g. stroking or scratching the skin)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pain in extremity
Panic disorder
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 28.57%
Pulmonary Tuberculosis (lungs tuberculosis): 3 people, 21.43%
Breast Cancer: 3 people, 21.43%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 3 people, 21.43%
High Blood Pressure: 2 people, 14.29%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 14.29%
Cardiac Disorder: 2 people, 14.29%
Dyspnea (difficult or laboured breathing): 1 person, 7.14%
Autoimmune Hepatitis: 1 person, 7.14%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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