Duexis and Diclofenac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duexis (famotidine; ibuprofen) and Diclofenac (diclofenac). Common drug interactions include abdominal pain upper among females and erectile dysfunction among males.

The phase IV clinical study analyzes what interactions people have when they take Duexis and Diclofenac. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Duexis?

Duexis has active ingredients of famotidine; ibuprofen. It is often used in arthritis. eHealthMe is studying from 1,731 Duexis users. Check the latest studies of Duexis.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.



On Jul, 12, 2026

13 people who take Duexis and Diclofenac together, and have interactions are studied.

Duexis and Diclofenac drug interactions.

What are the common drug interactions of Duexis and Diclofenac, by gender? *:

female:

  1. Abdominal pain upper
  2. Fatigue (feeling of tiredness)
  3. Abdominal distension
  4. Ankle fracture
  5. Blood cholesterol increased
  6. Blood pressure increased
  7. Chronic kidney disease
  8. Diarrhoea
  9. Dizziness
  10. Fall

male:

  1. Erectile dysfunction
  2. Back pain
  3. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  4. Chronic kidney disease
  5. Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
  6. Hypercholesterolaemia (high levels of cholesterol in the blood)
  7. Hyperlipidaemia (presence of excess lipids in the blood)
  8. Hypertension (high blood pressure)
  9. Protein urine
  10. Stress

What are the common drug interactions of Duexis and Diclofenac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Erectile dysfunction
  2. Back pain
  3. Chronic kidney disease
  4. Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
  5. Hypercholesterolaemia (high levels of cholesterol in the blood)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Hypertension (high blood pressure)
  8. Protein urine
  9. Stress

40-49:

  1. Back disorder
  2. Chronic kidney disease
  3. Foot deformity (functional disability of foot)
  4. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  5. Osteomyelitis (infection of bone)
  6. Shoulder operation

50-59:

  1. Feeling jittery
  2. Nervousness

60+:

  1. Fatigue (feeling of tiredness)
  2. Abdominal distension
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Hypotension (abnormally low blood pressure)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Therapeutic response unexpected
  8. Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
  9. Abdominal pain upper
  10. Ankle fracture

What are the existing conditions these people have? *

  1. Pain: 5 people, 38.46%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 30.77%
  4. Infection: 2 people, 15.38%
  5. Headache (pain in head): 2 people, 15.38%
  6. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 15.38%
  7. Fever: 2 people, 15.38%
  8. Joint Pain: 2 people, 15.38%
  9. Depression: 1 person, 7.69%
  10. Growth Hormone Deficiency: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Duexis and Diclofenac?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Duexis and Diclofenac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duexis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diclofenac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duexis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diclofenac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on famotidine; ibuprofen and diclofenac (the active ingredients of Duexis and Diclofenac, respectively), and Duexis and Diclofenac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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