Dulcolax and Aprepitant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dulcolax (bisacodyl) and Aprepitant (aprepitant). Common drug interactions include pain among females and abdominal abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Aprepitant. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

On Jul, 11, 2026

15 people who take Dulcolax and Aprepitant together, and have interactions are studied.

Dulcolax and Aprepitant drug interactions.

What are the common drug interactions of Dulcolax and Aprepitant, by gender? *:

female:

Pain
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Mouth haemorrhage (bleeding from mouth)
Oral pain
Stomatitis (inflammation of mucous membrane of mouth)
Anaemia (lack of blood)
Cardiac arrest
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Leukopenia (less number of white blood cells in blood)

male:

Abdominal abscess (collection of pus in abdomen)
Renal salt-wasting syndrome (lack of sodium due to excess excretion in urine)
Urinary retention (the inability to completely or partially empty the bladder)
Diarrhoea
Dysuria (painful or difficult urination)
Renal impairment (severely reduced kidney function)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Nausea (feeling of having an urge to vomit)
Non-small cell lung cancer (type of epithelial lung cancer)
Vomiting

What are the common drug interactions of Dulcolax and Aprepitant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Anaemia (lack of blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Vaginal haemorrhage (vaginal bleeding)
Weight decreased
Small intestinal obstruction (blockage in small intestine)

40-49:

Foot fracture

50-59:

Urinary retention (the inability to completely or partially empty the bladder)
Cardiac arrest
Muscular weakness (muscle weakness)
Diarrhoea
Dysuria (painful or difficult urination)
Renal impairment (severely reduced kidney function)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal abscess (collection of pus in abdomen)
Mouth haemorrhage (bleeding from mouth)
Oral pain

60+:

Nausea (feeling of having an urge to vomit)
Non-small cell lung cancer (type of epithelial lung cancer)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Skin exfoliation (removal of the oldest dead skin cells)
Vomiting

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 33.33%
Fever: 4 people, 26.67%
Nausea (feeling of having an urge to vomit): 4 people, 26.67%
Ovarian Cancer (cancer of ovary): 3 people, 20.00%
Nausea And Vomiting: 3 people, 20.00%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 13.33%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 2 people, 13.33%
Colon Cancer: 2 people, 13.33%
Head Injury: 2 people, 13.33%
Headache (pain in head): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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