Dulcolax and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dulcolax (bisacodyl) and Bumex (bumetanide). Common drug interactions include diverticulum intestinal haemorrhagic among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Bumex. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

52 people who take Dulcolax and Bumex together, and have interactions are studied.

What are the common drug interactions of Dulcolax and Bumex, by gender? *:

female:

Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Pleural effusion (water on the lungs)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

male:

Cardiac failure congestive
Pneumonia
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Troponin increased
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
Weight increased
Acute respiratory failure
Asthenia (weakness)
Death

What are the common drug interactions of Dulcolax and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaphylactic reaction (serious allergic reaction)

30-39:

n/a

40-49:

n/a

50-59:

Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Death
Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Enterocolonic fistula
Fatigue (feeling of tiredness)
Hypoxia (low oxygen in tissues)
Incision site cellulitis (spreading bacterial skin infection at incision site)
Incision site erythema (redness of the skin at incision site)

60+:

Cardiac failure congestive
Death
Fractured ischium
Oedema (fluid collection in tissue)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Troponin increased
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
Weight increased
Anaemia (lack of blood)

What are the existing conditions these people have? *

Pain: 8 people, 15.38%
Multiple Myeloma (cancer of the plasma cells): 6 people, 11.54%
Insomnia (sleeplessness): 5 people, 9.62%
Nausea (feeling of having an urge to vomit): 5 people, 9.62%
Stress And Anxiety: 4 people, 7.69%
Sleep Disorder: 4 people, 7.69%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 7.69%
High Blood Cholesterol: 4 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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