Dulcolax and Diclofenac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dulcolax (bisacodyl) and Diclofenac (diclofenac). Common drug interactions include abdominal pain among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Diclofenac. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.

On Jul, 14, 2026

84 people who take Dulcolax and Diclofenac together, and have interactions are studied.

Dulcolax and Diclofenac drug interactions.

What are the common drug interactions of Dulcolax and Diclofenac, by gender? *:

female:

Abdominal pain
Abdominal pain upper
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Blood urea increased
Brain natriuretic peptide increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Cellulitis (infection under the skin)

male:

Dyspnoea (difficult or laboured respiration)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Decreased appetite
Depression
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
General physical health deterioration (weak health status)
Hypersomnia (excessive daytime sleepiness (eds))
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Dulcolax and Diclofenac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Death
Suicidal ideation
Anxiety
Depression
Hypnopompic hallucination
Hypoaesthesia (reduced sense of touch or sensation)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Panic attack
Sleep paralysis (waking up and unable to move or speak)

20-29:

Post procedural complication
Retching (strong involuntary effort to vomit)
Skin irritation
Urethral polyp

30-39:

Decreased appetite
Depression
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
General physical health deterioration (weak health status)
Hypersomnia (excessive daytime sleepiness (eds))
Dysphagia (a condition in which swallowing is difficult or painful)
Lung neoplasm malignant (cancer tumour of lung)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Tongue disorder (disease of tongue)

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dyspnoea (difficult or laboured respiration)
Muscular weakness (muscle weakness)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Asthenia (weakness)
Diarrhoea
Urinary tract infection
Abdominal pain
Acute respiratory failure
Alopecia (absence of hair from areas of the body)

50-59:

Vomiting
Chronic kidney disease
Drug ineffective
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hyperkalaemia (damage to or disease of the kidney)
Loss of consciousness
Migraine (headache)
Nausea (feeling of having an urge to vomit)

60+:

Chronic kidney disease
Death
Blood pressure increased
Gait disturbance
Nausea (feeling of having an urge to vomit)
Nephropathy (damage to or disease of a kidney)
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)
Laryngitis (inflammation of the larynx)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 25.00%
Insomnia (sleeplessness): 16 people, 19.05%
Indigestion: 15 people, 17.86%
Pain: 13 people, 15.48%
Diabetes: 12 people, 14.29%
Dyspnea (difficult or laboured breathing): 12 people, 14.29%
Pancreatic Carcinoma (pancreatic cancer): 11 people, 13.10%
Abdominal Pain: 11 people, 13.10%
Depression: 10 people, 11.90%
High Blood Pressure: 9 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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