Dulcolax and Maxalt drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dulcolax (bisacodyl) and Maxalt (rizatriptan benzoate). Common drug interactions include pyrexia among females and dizziness among males.
The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Maxalt. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Dulcolax?
Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.
What is Maxalt?
Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.
45 people who take Dulcolax and Maxalt together, and have interactions are studied.

What are the common drug interactions of Dulcolax and Maxalt, by gender? *:
female:
- Pyrexia (fever)
- Sensory disturbance (sense disturbance)
- Chronic kidney disease
- Dry skin
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Hypokalaemia (low potassium)
- Laceration (tearing of soft body tissue)
- Localised infection (infection at the single location)
male:
- Dizziness
- Fall
- Dysarthria (speech disorder)
- Memory impairment
- Muscular weakness (muscle weakness)
- Neuropathy peripheral (surface nerve damage)
- Pain
- Pneumonia
- Tremor (trembling or shaking movements in one or more parts of your body)
- Abdominal discomfort
What are the common drug interactions of Dulcolax and Maxalt, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Distal intestinal obstruction syndrome (blockage of the intestines by thickened stool and occurs in individuals with cystic fibrosis)
20-29:
- Altered state of consciousness (altered state of mind)
- Cerebellar ataxia (loss of coordination)
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Balance disorder
- Concussion (short loss of normal brain function in response to a head injury)
- Dizziness
- Dysarthria (speech disorder)
- Fall
- Headache (pain in head)
30-39:
- Heart rate increased
- Hypotension (abnormally low blood pressure)
- Impaired gastric emptying
- Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
40-49:
- Dyskinesia (abnormality or impairment of voluntary movement)
- Pain
- Pyrexia (fever)
- Akathisia (a movement disorder characterized by a feeling of inner restlessness)
- Bartholin's cyst (cyst is formed on one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dystonia (abnormal muscle tone)
- Emotional disorder
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Family stress
50-59:
- Breast cancer stage iv
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cerebellar infarction (impaired blood circulation to cerebellum)
- Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
- Cerebral artery stenosis (hardening of brain blood vessels)
- Cerebral ventricle dilatation (enlargement of ventricle of brain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Clumsiness (a lack of coordination or elegance)
60+:
- Drug ineffective
- Fall
- Pain in extremity
- Peripheral swelling
- Poor quality sleep
- Rash papular (redness with papule)
- Renal impairment (severely reduced kidney function)
- Renal pain (kidney pain)
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
- Sensory disturbance (sense disturbance)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 20.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 17.78%
- Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 15.56%
- Nausea (feeling of having an urge to vomit): 7 people, 15.56%
- Stress And Anxiety: 6 people, 13.33%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 13.33%
- Headache (pain in head): 6 people, 13.33%
- Pain: 5 people, 11.11%
- High Blood Pressure: 5 people, 11.11%
- Insomnia (sleeplessness): 4 people, 8.89%
* Approximation only. Some reports may have incomplete information.
Do you take Dulcolax and Maxalt?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dulcolax and Maxalt:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dulcolax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Maxalt:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dulcolax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxalt and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bisacodyl and rizatriptan benzoate (the active ingredients of Dulcolax and Maxalt, respectively), and Dulcolax and Maxalt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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