Dulcolax and Motegrity drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dulcolax (bisacodyl) and Motegrity (prucalopride succinate). Common drug interactions include pain among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Motegrity. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Dulcolax?
Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.
What is Motegrity?
Motegrity has active ingredients of prucalopride succinate. eHealthMe is studying from 1,380 Motegrity users. Check the latest studies of Motegrity.
23 people who take Dulcolax and Motegrity together, and have interactions are studied.

What are the common drug interactions of Dulcolax and Motegrity, by gender? *:
female:
- Pain
- Depressed mood
- Pruritus (severe itching of the skin)
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
- Paranasal sinus discomfort
- Rhinorrhoea (watery mucus discharge from the nose)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
- Abdominal distension
- Abdominal pain
male:
- Diarrhoea
- Abdominal discomfort
- Gastric cancer (stomach cancer)
- Overdose
What are the common drug interactions of Dulcolax and Motegrity, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Headache (pain in head)
- Paranasal sinus discomfort
30-39:
n/a
40-49:
n/a
50-59:
- Post procedural complication
60+:
- Diarrhoea
- Drug ineffective
- Confusional state
- Gastric cancer (stomach cancer)
- Overdose
- Sleep talking (talking during sleeping)
What are the existing conditions these people have? *
- Irritable Bowel Syndrome: 5 people, 21.74%
- Idiopathic Generalised Epilepsy (epileptic disorders that are believed to have a strong underlying genetic basis): 2 people, 8.70%
- Cystic Fibrosis (disease of the secretary glands): 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Dulcolax and Motegrity?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Dulcolax and Motegrity:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dulcolax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Motegrity:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dulcolax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Motegrity and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bisacodyl and prucalopride succinate (the active ingredients of Dulcolax and Motegrity, respectively), and Dulcolax and Motegrity (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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