Dulcolax and Robaxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dulcolax (bisacodyl) and Robaxin (methocarbamol). Common drug interactions include osteoporosis among females and infection among males.

The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Robaxin. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

71 people who take Dulcolax and Robaxin together, and have interactions are studied.

What are the common drug interactions of Dulcolax and Robaxin, by gender? *:

female:

Osteoporosis (bones weak and more likely to break)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Rib fracture
Swelling
Swelling face
Throat tightness
Vomiting
Aphasia (damage to the parts of the brain that control language)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Infection
Anaemia (lack of blood)
Hernia pain
Incisional hernia (hernia caused by an incompletely-healed surgical wound)
Renal cancer (cancer of kidney)
Testicular disorder (disease of testes)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Autoimmune hepatitis
Bipolar disorder (mood disorder)

What are the common drug interactions of Dulcolax and Robaxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Road traffic accident
Bipolar disorder (mood disorder)
Chest pain
Drug ineffective
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Foot fracture
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Infection
Intervertebral disc protrusion (spinal disc protrusion)
Malaise (a feeling of general discomfort or uneasiness)

30-39:

Bedridden
Pyrexia (fever)
Septic shock (shock due to blood infection)
Urinary tract infection
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Foot fracture
Arthralgia (joint pain)
Emotional distress
Pain
Anxiety
Chronic kidney disease
Drug ineffective
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

50-59:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure increased
Bone pain
Chest discomfort
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Dry mouth
Ear pain
Escherichia sepsis (bacterial infection by escherichia coli)
Fatigue (feeling of tiredness)

60+:

Fall
Dry skin
Erythema (redness of the skin)
Laceration (tearing of soft body tissue)
Localised infection (infection at the single location)
Neuralgia (pain in one or more nerves)
Peripheral swelling
Poor quality sleep
Rash papular (redness with papule)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Pain: 17 people, 23.94%
Nausea (feeling of having an urge to vomit): 15 people, 21.13%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 18.31%
High Blood Pressure: 10 people, 14.08%
Migraine (headache): 8 people, 11.27%
High Blood Cholesterol: 7 people, 9.86%
Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 8.45%
Joint Pain: 5 people, 7.04%
Immunodeficiency Common Variable: 5 people, 7.04%
Stress And Anxiety: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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