Duoneb and Actigall drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Duoneb (albuterol sulfate; ipratropium bromide) and Actigall (ursodiol). Common drug interactions include blood cholesterol increased among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Duoneb and Actigall. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Duoneb?
Duoneb has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 8,093 Duoneb users. Check the latest studies of Duoneb.
What is Actigall?
Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.
24 people who take Duoneb and Actigall together, and have interactions are studied.

What are the common drug interactions of Duoneb and Actigall, by gender? *:
female:
- Blood cholesterol increased
- Cholecystitis chronic (long lasting infection of gallbladder)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Gallbladder operation
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Leukoplakia (white and gray patches inside the mouth)
- Sensation of foreign body
- Type 2 diabetes mellitus
- Vocal cord polyp
- Acute respiratory distress syndrome
male:
- Dyspnoea (difficult or laboured respiration)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Blood urea increased
- Bronchial haemorrhage (bleeding in bronchia)
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Constipation
- Cystic fibrosis (disease of the secretary glands)
- Diarrhoea
- Dysphagia (a condition in which swallowing is difficult or painful)
- Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
What are the common drug interactions of Duoneb and Actigall, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Staphylococcal bacteraemia (a bacterial infection of blood)
- Weight decreased
- Device related infection
- Drug ineffective
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Multi-organ failure (multisystem organ failure)
- Mycobacterium abscessus infection (rapid growing bacterial infection)
- Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Renal failure (kidney dysfunction)
20-29:
n/a
30-39:
- Pyrexia (fever)
- Acidosis (build-up of carbon dioxide in the blood)
- Acute respiratory distress syndrome
- Anaemia (lack of blood)
- Asthenia (weakness)
- Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
- Blood creatinine increased
- Blood urea increased
- Bronchial haemorrhage (bleeding in bronchia)
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
40-49:
- Cough
- Dyspnoea exertional (breathlessness or shortness of breath)
50-59:
- Anaphylactic reaction (serious allergic reaction)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Dyspnoea (difficult or laboured respiration)
- Eye pruritus (eye itching)
- Eye swelling
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Laryngeal oedema (swelling of larynx)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Throat irritation
- Blood cholesterol increased
60+:
- Death
- Ammonia increased
- Blood calcium decreased
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
- Epistaxis (bleed from the nose)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hepatic enzyme increased
- Insomnia (sleeplessness)
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Pruritus (severe itching of the skin)
What are the existing conditions these people have? *
- High Blood Pressure: 15 people, 62.50%
- Pain: 13 people, 54.17%
- Wheezing (a high-pitched whistling sound made while you breath): 11 people, 45.83%
- Cystic Fibrosis (disease of the secretary glands): 11 people, 45.83%
- Nausea (feeling of having an urge to vomit): 10 people, 41.67%
- Nasal Discomfort: 10 people, 41.67%
- Inflammation: 9 people, 37.50%
- Fungal Infection: 9 people, 37.50%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 9 people, 37.50%
- Blood Glucose Decreased: 9 people, 37.50%
* Approximation only. Some reports may have incomplete information.
Do you take Duoneb and Actigall?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Duoneb and Actigall:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Duoneb:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actigall:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Duoneb and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actigall and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and ursodiol (the active ingredients of Duoneb and Actigall, respectively), and Duoneb and Actigall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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